Evidence map›Paper›PMID 41300792›Full record

ArticleGenes2025

Integrated Transcriptomic and Metabolomic Analyses Reveal Key Genes Involved in Phenylpropanoid Metabolism in

Zhengchun Li, Zijing Zhou, Hua Feng, Yong Wang, Zhaohua Zeng, Qiandong Hou, Luonan Shen

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhengchun LiKey Laboratory of Conservation, Development and Utilization of Karst Characteristic Biological Resources, Department of Modern Agriculture, Zunyi Vocational and Technical College, Zunyi 563006, China.ORCID 0000-0001-8636-3328
Zijing ZhouInstitute for Forest Resources & Environment of Guizhou/College of Forestry, Guizhou University, Guiyang 550025, China.
Hua FengKey Laboratory of Conservation, Development and Utilization of Karst Characteristic Biological Resources, Department of Modern Agriculture, Zunyi Vocational and Technical College, Zunyi 563006, China.
Yong WangKey Laboratory of Conservation, Development and Utilization of Karst Characteristic Biological Resources, Department of Modern Agriculture, Zunyi Vocational and Technical College, Zunyi 563006, China.
Zhaohua ZengKey Laboratory of Conservation, Development and Utilization of Karst Characteristic Biological Resources, Department of Modern Agriculture, Zunyi Vocational and Technical College, Zunyi 563006, China.
Qiandong HouSchool of Ethnic-Minority Medicine, Guizhou Minzu University, Guiyang 550025, China.
Luonan ShenInstitute for Forest Resources & Environment of Guizhou/College of Forestry, Guizhou University, Guiyang 550025, China.

Funding

2024 Guizhou Provincial Employee Innovation Grant Project (Selection of Elite Plants and Research on High-Yield Cultivation Techniques for Guizhou-Genuine Medicinal Herb Lonicera macranthoides), and Zunyi Vocational and Technical College High-Level Talent Zunzhike Talent[2025]No.3Guizhou Association for Science and Technology "Xinzhi Qianyan" Leading Project 2025XZQYXM-01-27Zunyi Science and Technology Innovation Talent Team Project Zunshike Talent[2024]No.3Zunyi Science and Technology Plant Project Zunshikehe HZ Zi[2024]No.156
6 · The paper itself

Abstract

background

methodsIntegrated transcriptomic and metabolomic analyses were conducted across three floral developmental stages: flower bud (FB), white flower (WF), and golden flower (GF).

resultsClustering analysis revealed distinct molecular profiles, with the WF and GF stages clustering together and clearly separating from the FB stage. The most significant metabolomic variation was observed between the GF and FB stages. KEGG enrichment analysis consistently highlighted the phenylpropanoid biosynthesis pathway as a key hub. Stage-specific accumulation patterns were identified for critical metabolites: caffeoylquinic acid peaked at the WF stage, while ferulic acid, sinapic acid, cinnamic acid, and p-coumaric acid reached their highest levels at the GF stage. Within this pathway, we identified 11 DEGs encoding the core enzymes, alongside 15 associated DAMs. The expression trends of four

conclusionsThis study deciphers the stage-specific regulatory network of CGA biosynthesis, providing critical insights and genetic resources for cultivating high-medicinal-content varieties of

Indexed as

FlowersLoniceraPlant ProteinsTranscriptomeChlorogenic AcidGene Expression ProfilingGene Expression Regulation, PlantMetabolomeMetabolomicsPhenylpropionatesPropanolsChlorogenic AcidPhenylpropionatesPlant ProteinsPropanolschlorogenic acids (CGAs)Lonicera macranthoidesmetabolomephenylpropanoid biosynthesistranscriptome

Identifiers

PMID41300792
PMCPMC12651994

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.