Evidence map›Paper›PMID 41300763›Full record

ArticleGenes2025

Exome Sequencing Uncovers Genetic Drivers of Multiple Sclerosis in a Multiplex Family.

Carla Lintas, Simone Bonora, Anna Marabotti, Claudio Tabolacci, Maria Luisa Scattoni, Fioravante Capone, Mariagrazia Rossi, Vincenzo Di Lazzaro, Fiorella Gurrieri

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carla LintasResearch Unit of Medical Genetics, Department of Medicine, University Campus-Biomedico of Rome, 00128 Roma, Italy.ORCID 0000-0003-1209-8554
Simone BonoraDepartment of Chemistry and Biology "A. Zambelli", University of Salerno, 84084 Fisciano, SA, Italy.ORCID 0009-0001-2620-1252
Anna MarabottiDepartment of Chemistry and Biology "A. Zambelli", University of Salerno, 84084 Fisciano, SA, Italy.ORCID 0000-0002-9510-5205
Claudio TabolacciCoordination and Promotion of Research, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.ORCID 0000-0001-5001-285X
Maria Luisa ScattoniCoordination and Promotion of Research, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.ORCID 0000-0002-6659-0280
Fioravante CaponeOperative Research Unit of Neurology, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Roma, Italy.
Mariagrazia RossiOperative Research Unit of Neurology, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Roma, Italy.
Vincenzo Di LazzaroOperative Research Unit of Neurology, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Roma, Italy.ORCID 0000-0002-9113-5925
Fiorella GurrieriResearch Unit of Medical Genetics, Department of Medicine, University Campus-Biomedico of Rome, 00128 Roma, Italy.ORCID 0000-0002-6775-5972

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Exome SequencingMultiple SclerosisAdultAgedExomeFamilyFemaleHumansMaleMiddle AgedPedigreeProtein Conformationcausative genesfamilial multiple sclerosisgerminalwhole exome sequencing

Identifiers

PMID41300763
PMCPMC12652177

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.