Evidence map›Paper›PMID 41300755›Full record

ArticleGenes2025

Genetic Association Study of Brain-Derived Neurotrophic Factor (BDNF) and Serotonin-Related Gene Variants in Suicide Attempters with Major Depressive Disorder and Control Persons.

Taehun Kim, Seong Beom Oh, Han Joo Choi, Chan Young Koh, Yong Oh Kim, Min Jeong Kim, Sijun Woo, Youngil Lee, Chang Min Lee, Jong Wan Kim and 2 more

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Taehun KimDepartment of Emergency, Graduate School, Dankook University, Cheonan 31116, Republic of Korea.
Seong Beom OhDepartment of Emergency, Graduate School, Dankook University, Cheonan 31116, Republic of Korea.
Han Joo ChoiDepartment of Emergency, Graduate School, Dankook University, Cheonan 31116, Republic of Korea.
Chan Young KohDepartment of Emergency, Graduate School, Dankook University, Cheonan 31116, Republic of Korea.
Yong Oh KimDepartment of Emergency, Graduate School, Dankook University, Cheonan 31116, Republic of Korea.
Min Jeong KimDepartment of Emergency, Graduate School, Dankook University, Cheonan 31116, Republic of Korea.
Sijun WooDepartment of Emergency, Graduate School, Dankook University, Cheonan 31116, Republic of Korea.
Youngil LeeDepartment of Anatomy, College of Medicine, Dankook University, Cheonan 31116, Republic of Korea.ORCID 0000-0001-6749-156X
Chang Min LeeDepartment of Neurology, College of Medicine, Dankook University, Cheonan 31116, Republic of Korea.ORCID 0000-0001-9947-5791
Jong Wan KimDepartment of Laboratory Medicine, College of Medicine, Dankook University, Cheonan 31116, Republic of Korea.
You-Shin YiDepartment of Psychology and Psychotheray, College of Health Science, Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Republic of Korea.
Myung Ho LimDepartment of Psychology and Psychotheray, College of Health Science, Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Republic of Korea.ORCID 0000-0001-5370-4376

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSuicide attempts have become one of the most serious problems worldwide in recent years. Suicide attempts are known to be genetically highly associated with serotonin and BDNF in international studies.

methodsIn this study, we investigated the association with rs6265 (

resultsA case-control study was conducted with 226 suicide and suicide attempts with major depressive disorder and 1469 general controls, and genotypes were determined by PCR-RFLP method. Significant associations between the rs11030101 (

conclusionsThe

Indexed as

Brain-Derived Neurotrophic FactorMajor Depressive DisorderPolymorphism, Single NucleotideSerotoninSerotonin Plasma Membrane Transport ProteinsSuicide, AttemptedAdultCase-Control StudiesFemaleGenetic Association StudiesGenetic Predisposition to DiseaseGenotypeHumansMaleMiddle AgedReceptor, Serotonin, 5-HT2ABDNF protein, humanBrain-Derived Neurotrophic FactorReceptor, Serotonin, 5-HT2ASerotoninSerotonin Plasma Membrane Transport ProteinsSLC6A4 protein, humanBDNF SLC6A4HTR2Amajor depressive disordersuicidesuicide attemptTPH

Identifiers

PMID41300755
PMCPMC12652185

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.