Evidence map›Paper›PMID 41300713›Full record

Observational studyGenes2025

Towards Personalized Chemotherapy in Gastrointestinal Cancers: Prospective Analysis of Pharmacogenetic Variants in a Russian Cohort.

Denis Fedorinov, Vladimir Lyadov, Marina Lyadova, Sherzod Abdullaev, Anastasia Kachanova, Rustam Heydarov, Igor Shashkov, Sergey Surzhikov, Vladimir Mikhailovich, Dmitry Sychev

Abstract readObservational Study
In one paragraph

Observational study in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Denis FedorinovFederal State Budgetary Educational Institution, Further Professional Education "Russian Medical Academy of Continuous Professional Education", the Ministry of Healthcare of the Russian Federation, 123242 Moscow, Russia.ORCID 0000-0001-5516-7367
Vladimir LyadovFederal State Budgetary Educational Institution, Further Professional Education "Russian Medical Academy of Continuous Professional Education", the Ministry of Healthcare of the Russian Federation, 123242 Moscow, Russia.ORCID 0000-0002-7281-3591
Marina LyadovaMoscow State Budgetary Healthcare Institution "Oncological Center No. 1 of Moscow City Hospital Named After S.S. Yudin, Moscow Healthcare Department", 115446 Moscow, Russia.ORCID 0000-0002-9558-5579
Sherzod AbdullaevFederal State Budgetary Educational Institution, Further Professional Education "Russian Medical Academy of Continuous Professional Education", the Ministry of Healthcare of the Russian Federation, 123242 Moscow, Russia.ORCID 0000-0001-9001-1499
Anastasia KachanovaFederal State Budgetary Educational Institution, Further Professional Education "Russian Medical Academy of Continuous Professional Education", the Ministry of Healthcare of the Russian Federation, 123242 Moscow, Russia.ORCID 0000-0003-3194-4410
Rustam HeydarovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-4971-2629
Igor ShashkovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0001-6037-730X
Sergey SurzhikovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-6043-1182
Vladimir MikhailovichEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0003-4894-1304
Dmitry SychevFederal State Budgetary Educational Institution, Further Professional Education "Russian Medical Academy of Continuous Professional Education", the Ministry of Healthcare of the Russian Federation, 123242 Moscow, Russia.ORCID 0000-0002-4496-3680

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2025-463
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gastrointestinal NeoplasmsPharmacogenomic VariantsPrecision MedicineAdultAgedFemaleGene FrequencyGlucuronosyltransferaseHumansMaleMiddle AgedPharmacogeneticsPharmacogenomic TestingPolymorphism, Single NucleotideProspective StudiesRussiaGlucuronosyltransferaseUGT1A1 EnzymecancerDPYDgenegeneticsgenomegenotypepharmacogeneticspharmacogenomicsUGT1A1

Identifiers

PMID41300713
PMCPMC12652166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.