Evidence map›Paper›PMID 41300657›Full record

ArticleChildren (Basel, Switzerland)2025

Neonatal Pyruvate Kinase Deficiency Presenting with Severe Hemolytic Anemia and Liver Failure.

Yung-Han Hsu, Chuen-Bin Jiang, Jen-Yin Hou, Wai-Tim Jim, Shuan-Pei Lin, Szu-Wen Chang, Kai-Ti Tseng, Ni-Chung Lee

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yung-Han HsuDepartment of Pediatrics, Hsinchu Municipal MacKay Children's Hospital, Hsinchu City 300046, Taiwan.
Chuen-Bin JiangDepartment of Pediatric Gastroenterology, Hepatology and Nutrition, MacKay Children's Hospital, Taipei City 104217, Taiwan.ORCID 0000-0003-2763-3476
Jen-Yin HouDivision of Pediatric Hematology-Oncology, MacKay Children's Hospital, Taipei City 104217, Taiwan.
Wai-Tim JimDivision of Neonatology, Department of Pediatrics, MacKay Children's Hospital, Taipei City 104217, Taiwan.
Shuan-Pei LinDepartment of Medicine, MacKay Medical College, MacKay Medical University, New Taipei City 252005, Taiwan.
Szu-Wen ChangDepartment of Pediatric Gastroenterology, Hepatology and Nutrition, MacKay Children's Hospital, Taipei City 104217, Taiwan.
Kai-Ti TsengDivision of Neonatology, Department of Pediatrics, MacKay Memorial Hospital Tamshui Branch, New Taipei City 251404, Taiwan.ORCID 0009-0008-4234-772X
Ni-Chung LeeDepartment of Medical Genetics, National Taiwan University Hospital, Taipei City 100225, Taiwan.ORCID 0000-0002-5011-7499

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

conjugated hyperbilirubinemiagenetic diagnosishemolytic anemiahepatic involvementiron overloadneonatal liver failurePKLR mutationpyruvate kinase deficiency

Identifiers

PMID41300657
PMCPMC12651929

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.