ArticleAntioxidants (Basel, Switzerland)2025
Evaluation of the Anticancer Activity of Medicinal Plants Predominantly Accumulating Ellagic Acid Compounds.
Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Comparative Phytochemical Profiling and Biological Activities of TwoMolecules (Basel, Switzerland) · 2026Article
- Degraded sulfated galactan derived fromMolecular medicine reports · 2026Article
- Multitarget Antiproliferative Activity ofMolecules (Basel, Switzerland) · 2026Article
- Extraction Strategy and C18 Solid-Phase Fractionation Shape Phenolic Profiles, Antioxidant Capacity, and Cancer Cell Antiproliferative Activity of Selected Medicinal Plants.Antioxidants (Basel, Switzerland) · 2026Article
- Enzyme-Assisted Extraction of Bioactive Compounds fromPlants (Basel, Switzerland) · 2026Article
- Evaluation of the Antibacterial, Antioxidant, Anticancer, and Antidiabetic Activities of the Leaves and Inflorescences ofBiomedicines · 2026Article
- Advances on Ethnobotanical, Phytochemical, and Preclinical Studies ofJournal of experimental pharmacology · 2026Review
- Innovations in the Delivery of Bioactive Compounds for Cancer Prevention and Therapy: Advances, Challenges, and Future Perspectives.Pharmaceuticals (Basel, Switzerland) · 2025Review
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
Cancer remains a major global health challenge, prompting the search for natural therapeutic agents with selective anticancer activity. This study investigated extracts from 12 medicinal plant species (a total of 21 samples) rich in phenolic compounds, particularly ellagic acid and its derivatives, to evaluate their antioxidant properties and ability to inhibit cancer cell viability. Spectrometric analysis and high-performance liquid chromatography (HPLC) with electrochemical detection (ED) and ultraviolet-visible (UV-VIS) detection were used for compound identification. The anticancer activity of plant extracts was tested using the MTS cell proliferation assay to determine anticancer activity on 4T1, A549, Caki-1, HCT116, and MCF7 cancer cell lines. The HEK-293 healthy cell line was used to determine extracts cytotoxicity. Study results indicate that black walnut (
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Registered trials
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