Evidence map›Paper›PMID 41300376›Full record

ArticleBiology2025

Soy Isoflavones Mitigate High-Fat Diet-Induced Oxidative Stress and Inflammation in the Gut of

Shao Wang, Minglang Cai, Quan Li, Huahong Wei, Yi Hu, Junzhi Zhang

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shao WangFisheries College, Hunan Agricultural University, Changsha 410128, China.ORCID 0009-0007-7699-3183
Minglang CaiFisheries College, Hunan Agricultural University, Changsha 410128, China.ORCID 0000-0002-8626-2209
Quan LiFisheries College, Hunan Agricultural University, Changsha 410128, China.ORCID 0009-0005-0531-7378
Huahong WeiFisheries College, Hunan Agricultural University, Changsha 410128, China.ORCID 0009-0003-6267-4991
Yi HuFisheries College, Hunan Agricultural University, Changsha 410128, China.ORCID 0000-0002-0185-9250
Junzhi ZhangFisheries College, Hunan Agricultural University, Changsha 410128, China.ORCID 0000-0002-4858-2869

Funding

National Natural Science Foundation of China 32202957Natural Science Foundation of Hunan Province 2023JJ40322Research Foundation of Education Bureau of Hunan Province 23B0184
6 · The paper itself

Abstract

High-fat diets are commonly used in eel aquaculture to reduce protein costs, but excessive fat intake can impair intestine health. This study investigated whether soy isoflavones (SIFs), an emulsifying additive, could mitigate the negative effects of high-fat diets in eel. Six hundred eels (30.00 g) were randomly divided into four groups with three replicates: control (CK, 5.96% fat), high-fat diet (HFD, 11.96% fat), and HFD supplemented with 50 mg/kg (LSF) or 100 mg/kg SIF (HSF) for 8 weeks. Results show that SIF supplementation reversed adverse effects on eels fed high-fat diets, reducing intestine damage (better villi development and lower malondialdehyde levels) and improving antioxidant capacity (higher glutathione,

Indexed as

gut microbiotahigh-fat dietinflammationMonopterus albusoxidative stresssoy isoflavone

Identifiers

PMID41300376
PMCPMC12650275

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.