Evidence map›Paper›PMID 41300090›Full record

ArticleFoods (Basel, Switzerland)2025

Chemical Mechanisms Underlying Sweetness Enhancement During Processing of Rehmanniae Radix: Carbohydrate Hydrolysis, Degradation of Bitter Compounds, and Interaction with Taste Receptors.

Wenting Zu, Jiasheng Wang, Jing Wang, Hongyue Wang, Liangliang Song, Yichen Li, Hongshuang Chi, Gaimei She, Hong Du

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenting ZuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Jiasheng WangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Jing WangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Hongyue WangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Liangliang SongSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Yichen LiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Hongshuang ChiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Gaimei SheSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.ORCID 0000-0003-1754-2140
Hong DuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.

Funding

the National Natural Science Foundation of China 82130113,82274206
6 · The paper itself

Abstract

Thermal processing is widely applied in food manufacturing to enhance flavor, but the mechanisms underlying taste transformation remain insufficiently understood. Rehmannia Radix, traditionally processed by steaming, undergoes a distinctive shift from bitterness to sweetness, serving as a representative model for flavor modulation during processing. In this study, sensory evaluation (n = 12), electronic tongue analysis, HPLC-based sugar and marker profiling across 17 batches, and molecular docking with representative human taste receptors were combined to investigate the mechanisms of taste transformation. The results showed that steaming markedly increased sweetness while reducing bitterness (

Indexed as

carbohydrate hydrolysisiridoid glycoside transformationRehmannia Radixsweetness enhancementtaste receptor interactionsthermal processing

Identifiers

PMID41300090
PMCPMC12651911

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.