Evidence map›Paper›PMID 41300012›Full record

ArticleFoods (Basel, Switzerland)2025

Impact of Drying and Storage Conditions on the Bioactive and Nutritional Properties of Malolactic Wine Lees.

Roberta Barreto de Andrade Bulos, Carolina Oliveira de Souza, Cedenir Pereira de Quadros, Otávio Augusto Durando Leme, Luiz Claudio Corrêa, Maria Beatriz Prior Pinto Oliveira, Susana Machado, Aline Camarão Telles Biasoto, Pedro Paulo Lordelo Guimarães Tavares, Renata Quartieri Nascimento and 1 more

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Roberta Barreto de Andrade BulosFood Science Postgraduate Program, Faculty of Pharmacy, Federal University of Bahia, Salvador 40170-100, BA, Brazil.ORCID 0000-0002-9727-9882
Carolina Oliveira de SouzaFood Science Postgraduate Program, Faculty of Pharmacy, Federal University of Bahia, Salvador 40170-100, BA, Brazil.ORCID 0000-0002-8028-5418
Cedenir Pereira de QuadrosSchool of Pharmacy, Federal University of the São Francisco Valley (UNIVASF), Petrolina 56300-000, PE, Brazil.
Otávio Augusto Durando LemeSchool of Pharmacy, Federal University of the São Francisco Valley (UNIVASF), Petrolina 56300-000, PE, Brazil.ORCID 0009-0005-1800-0628
Luiz Claudio CorrêaBrazilian Agricultural Research Corporation, Embrapa Semi-Arid, Petrolina 56302-970, PE, Brazil.ORCID 0000-0001-9877-6437
Maria Beatriz Prior Pinto OliveiraNetwork of Chemistry and Technology/Associated Laboratory for Green Chemistry (REQUIMTE/LAQV), Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-6767-6596
Susana MachadoNetwork of Chemistry and Technology/Associated Laboratory for Green Chemistry (REQUIMTE/LAQV), Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-4567-0687
Aline Camarão Telles BiasotoFood Science Postgraduate Program, Faculty of Pharmacy, Federal University of Bahia, Salvador 40170-100, BA, Brazil.ORCID 0000-0002-2424-2384
Pedro Paulo Lordelo Guimarães TavaresFood Science Postgraduate Program, Faculty of Pharmacy, Federal University of Bahia, Salvador 40170-100, BA, Brazil.ORCID 0000-0002-3621-9640
Renata Quartieri NascimentoFood Science Postgraduate Program, Faculty of Pharmacy, Federal University of Bahia, Salvador 40170-100, BA, Brazil.
Marcelo Andrés Umsza-GuezFood Science Postgraduate Program, Faculty of Pharmacy, Federal University of Bahia, Salvador 40170-100, BA, Brazil.ORCID 0000-0003-3145-6935

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wine lees, a winemaking by-product, have high potential for reuse due to their significant phenolic content and antioxidant capacity. To preserve their composition and enhance their feasibility for incorporation into food products, this study evaluated the effects of oven drying (40 °C) and freeze-drying on the physicochemical and nutritional characteristics of malolactic lees, as well as the impact of the storage time. Samples were analyzed at 0, 45, and 90 days of storage at 25 °C under light exposure conditions. Total phenolic content was determined by Folin-Ciocalteu, antioxidant activity by DPPH and FRAP assays, and phenolic groups by HPLC-DAD-FD. Both methods preserved a high protein content (~20%), with 44.66% essential amino acids and an essential amino acid index of 1.55, indicating high-quality proteins. The freeze-dried lees showed a higher phenolic content (77.92 mg GAE/g), whereas the oven-dried lees exhibited greater antioxidant activity, likely due to the formation or release of bound phenolic compounds induced by thermal processing. Among the phenolic groups, tannins were the most favored in terms of preservation. Storage time significantly influenced the parameters evaluated, indicating the impact of drying on stability. While freeze-drying better preserved phenolic compounds, oven drying was considered the most suitable option for large-scale application.

Indexed as

amino acidsby-product reusefreeze-dryingmalolactic fermentationovenwine lees

Identifiers

PMID41300012
PMCPMC12651660

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.