Evidence map›Paper›PMID 41299870›Full record

ArticleJournal of psychosocial oncology2026

Psychological flexibility, distress, and coping in ovarian cancer survivors.

Rachel Telles, Alexis Hosch, Kathryn P Pennington, Matthew Schlumbrecht, Bonnie A McGregor, Leslie Heron, Sharaf Zia, Alyssa Noble, Michael J Goodheart, Megan Noonan and 2 more

Abstract read
In one paragraph

Article in Journal of psychosocial oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rachel TellesDepartment of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, USA.
Alexis HoschDepartment of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, USA.
Kathryn P PenningtonDivision of Gynecologic Oncology, University of Washington Medical Center, Seattle, WA, USA.
Matthew SchlumbrechtDivision of Gynecologic Oncology, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA.
Bonnie A McGregorOrion Center for Integrative Medicine, Seattle, WA, USA.
Leslie HeronCancer Survivorship Provider Network, Seattle, WA, USA.
Sharaf ZiaDepartment of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, USA.
Alyssa NobleDepartment of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, USA.
Michael J GoodheartDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Iowa, Iowa City, IA, USA.
Megan NoonanDepartment of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, USA.
Frank J PenedoDivision of Gynecologic Oncology, University of Washington Medical Center, Seattle, WA, USA.
Susan K LutgendorfDepartment of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, USA.

Funding

The University of Iowa Clinical and Translational Science AwardUL1TR002537 · NCATS · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R, WINOKUR, PATRICIA · 2018 to 2022
$20.0M
Living Well: A Web-based Intervention to Improve Quality of Life in Rural and Urban Ovarian Cancer SurvivorsR01CA246540 · NCI · UNIVERSITY OF IOWA · PI LUTGENDORF, SUSAN K · 2020 to 2024
$3.0M
NCATS NIH HHS UL1 TR002537NCI NIH HHS R01 CA246540
6 · The paper itself

Abstract

backgroundOvarian cancer survivors report elevated levels of psychological distress due to the high rates of recurrence and mortality, but little is currently known about the coping skills and strengths that survivors draw upon during their cancer survivorship. One such possible strength is psychological flexibility, defined as the ability to stay in the present moment regardless of unpleasant experiences and make behavioral choices based on values.

objectiveThe study aimed to explore psychological flexibility and coping among ovarian cancer survivors prior to their participation in a web-based psychosocial intervention and to examine potential mediators of distress.

methodsOvarian cancer survivors were recruited to participate in an 11-week group-based, web-delivered psychosocial intervention. Participants completed assessments of mood, psychological flexibility and coping before the intervention. 165 ovarian cancer survivors provided survey data on psychosocial and clinical characteristics prior to randomization. Multiple mediation models were used to examine potential mediators in the relation of psychological flexibility with depression and anxiety.

resultsSurvivors reported mild levels of depression and anxiety. Multiple mediation models revealed significant indirect effects of psychological flexibility on both anxiety and depression. The negative association between psychological flexibility and anxiety was partially mediated by avoidant coping (

conclusionsPsychological flexibility is associated with less distress in ovarian cancer survivors who present for psychological intervention, and this pathway is partially mediated by avoidant coping and cancer-related worry. Mindfulness techniques and coping skills training may ameliorate these effects and improve psychological functioning.

Indexed as

Adaptation, PsychologicalCancer SurvivorsOvarian NeoplasmsPsychological DistressAdultAgedAnxietyDepressionFemaleHumansInternet-Based InterventionMiddle AgedPsychosocial InterventionCopingdepressionmindfulnessovarian cancer survivorspsychological flexibilityquality of life

Identifiers

PMID41299870
PMCPMC13187919

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.