Evidence map›Paper›PMID 41299640›Full record

ArticleBMC health services research2025

Understanding the cost of pharmacy-delivered HIV pre- and post-exposure prophylaxis service delivery in Kenya: findings from pilot studies.

Obinna I Ekwunife, Alexandra P Kuo, Preetika Banerjee, Shengruo Zhang, Catherine Kiptinness, Victor Omollo, Yilin Chen, Stephanie D Roche, Josephine Odoyo, Elizabeth Bukusi and 3 more

Abstract read
In one paragraph

Article in BMC health services research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Obinna I EkwunifePublic Health Sciences Division, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA, 98109, USA. ekwunife@buffalo.edu.
Alexandra P KuoPublic Health Sciences Division, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA, 98109, USA.
Preetika BanerjeePublic Health Sciences Division, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA, 98109, USA.
Shengruo ZhangDepartment of Epidemiology, University of Washington, Seattle, USA.
Catherine KiptinnessCenter for Clinical Research, Kenya Medical Research Institute, Thika, Kenya.
Victor OmolloKenya Medical Research Institute, Kisumu, Kenya.
Yilin ChenThe Comparative Health Outcomes, Policy and Economics (CHOICE) Institute, School of Pharmacy, University of Washington, Seattle, USA.
Stephanie D RochePublic Health Sciences Division, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA, 98109, USA.
Josephine OdoyoKenya Medical Research Institute, Kisumu, Kenya.
Elizabeth BukusiDepartment of Global Health, University of Washington, Seattle, USA.
Kenneth NgureDepartment of Global Health, University of Washington, Seattle, USA.
Monisha Sharma *Department of Global Health, University of Washington, Seattle, USA.
Katrina F Ortblad *Public Health Sciences Division, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, Seattle, WA, 98109, USA.

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI CONNIE L CELUM · 1988 to 2026
$104.9M
Pharmacy delivery to expand the reach of PrEP in KenyaR34MH120106 · NIMH · UNIVERSITY OF WASHINGTON · PI ORTBLAD, KATRINA FRANCES · 2019 to 2020
$605k
Gates Foundation INV-033052NIAID NIH HHS P30 AI027757NIH HHS R34 MH120106NIMH NIH HHS R34 MH120106
6 · The paper itself

Abstract

backgroundPrivate pharmacies are a primary access point for health services in many African countries. Leveraging private-sector pharmacies to deliver HIV prevention services, including pre- and post-exposure prophylaxis (PrEP/PEP), may expand the reach of these services. Understanding delivery costs is necessary to inform scale-up.

methodsWe used data from two pilot studies conducted in Kisumu County, Kenya. In the first pilot, pharmacy providers at 12 pharmacies delivered free PrEP/PEP to eligible clients (≥ 18 years) using a prescribing checklist with remote clinician oversight; PrEP/PEP drugs were donated from government stock. Using microcosting, we estimated the economic and financial costs from the provider's perspective for: (1) subsidized delivery (donated commodities excluded), and (2) non-subsidized delivery (donated commodities included). We also assessed client willingness to pay for PrEP services at pharmacies using PrEP client survey data. In the second pilot, pharmacy providers at 20 pharmacies delivered HIV testing services. We assessed providers' anticipated willingness to deliver PrEP services using provider survey data.

resultFrom February to July 2022, pharmacies in the first pilot recorded 1,564 PrEP/PEP visits, and initiated 691 clients on PrEP. Among clients eligible to continue PrEP at the pharmacy, 69% (479/691) refilled at least once. We collected 694 surveys from PrEP clients. From March to June 2022, 40 providers in the second pilot completed surveys. The estimated economic (financial) costs per client-month on PrEP were $3.66 ($2.17) USD for subsidized and $13.23 ($11.74) USD for non-subsidized delivery, and for PEP were $3.66 ($2.15) USD for subsidized and $10.75 ($9.24) USD for non-subsidized delivery. Most PrEP clients (83%, 575/691) expressed willingness to pay for pharmacy-delivered PrEP services; the median amount they were willing to pay per visit was $3.30 USD (IQR $1.60-$4.10 USD), which exceeded the median maximum amount providers said they would charge per visit ($2.40 USD, IQR $1.60-$4.10 USD).

conclusionsWhen subsidized with drugs from government stock, pharmacies are a low-cost platform for delivering PrEP and PEP services in Kenya. Client out-of-pocket payments could help sustain pharmacy PrEP/PEP delivery at scale, enabling broader coverage of HIV prevention services.

Indexed as

HIV InfectionsPharmaciesPost-Exposure ProphylaxisPre-Exposure ProphylaxisAdultAnti-HIV AgentsFemaleHumansKenyaMalePilot ProjectsAnti-HIV AgentsAfricaCostsDifferentiated service deliveryHIV preventionKenyaMicrocostingPharmaciesPrEP

Identifiers

PMID41299640
PMCPMC12659100

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.