Scoping review for treatment of osteolysis in total ankle arthroplasty.

Angela Seidel, Michael Li, Karl-Andre Lalonde, Risa Shorr, Bradley Meulenkamp

Abstract readScoping Review

In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Angela SeidelDivision of Orthopedic Surgery, The Ottawa Hospital, University of Ottawa, 1053 Carling Avenue, Ottawa, ON, K1Y 4E9, Canada. Angela.seidel@h-fr.ch.ORCID http://orcid.org/0000-0002-7759-2011

Michael LiDivision of Orthopedic Surgery, The Ottawa Hospital, University of Ottawa, 1053 Carling Avenue, Ottawa, ON, K1Y 4E9, Canada.ORCID http://orcid.org/0000-0001-6378-1578

Karl-Andre LalondeDivision of Orthopedic Surgery, The Ottawa Hospital, University of Ottawa, 1053 Carling Avenue, Ottawa, ON, K1Y 4E9, Canada.ORCID http://orcid.org/0000-0002-1634-6474

Risa ShorrMedical Librarian, The Ottawa Hospital, 1053 Carling Avenue, Ottawa, ON, K1Y 4E9, Canada.

Bradley MeulenkampDivision of Orthopedic Surgery, The Ottawa Hospital, University of Ottawa, 1053 Carling Avenue, Ottawa, ON, K1Y 4E9, Canada.ORCID http://orcid.org/0000-0001-8335-3677

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFollowing total ankle replacement (TAR), osteolysis is a known complication. No consensus exists regarding management.

methodsApplying the Arksey and O'Malley framework for scoping studies, a study protocol and a data extraction form was created. The research included all studies until March 2025. Study selection and data extraction were performed by two independent reviewers.

resultsTwo hundred and eighty-seven studies were identified, of which 54 studies (case series and case reports) were included. 69% of the studies included below 10 cases. The most common reported treatment was bone grafting in n = 36 (67%) of studies. The conversion of the TAR to an ankle fusion (n = 16 studies, 30%) was more frequent than the revision to a TAR (n = 15 studies, 28%). Eleven studies reported multiple treatment options. Long-term follow-up and standardized outcome measurements were infrequently discussed.

conclusionThis scoping review demonstrates that the existing literature is highly heterogeneous and insufficient to recommend standard treatment.

Indexed as

Ankle JointArthroplasty, Replacement, AnkleBone TransplantationOsteolysisPostoperative ComplicationsHumansReoperationTreatment OutcomeBone graftingCystsFusionOsteolysisRevision total ankle replacementTotal ankle replacementTreatment

Identifiers

PMID41299579

DOI10.1186/s12891-025-09278-4

PMCPMC12659475

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.