Evidence map›Paper›PMID 41299522›Full record

ArticleBMC women's health2025

Cervical cancer screening and treatment of VIA positive lesions among women living with HIV in Nairobi and Kajiado counties, Kenya: results from a targeted intervention implemented under the USAID Fahari ya Jamii project in supported HIV clinics.

Lulu Ndapatani, Elizabeth Kubo, Ashford Munene, Collins Odhiambo, Susan Arodi, Reson Marima, Annastacia Kumola, Dennis Osiemo, Teresa Simiyu, Jared Mecha and 1 more

Abstract read
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Article in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Lulu Ndapatani *Department of Clinical Medicine and Therapeutics, University of Nairobi School of Medicine - Fahari ya Jamii project, Nairobi, Kenya. lndapatani@gmail.com.
Elizabeth Kubo *Department of Clinical Medicine and Therapeutics, University of Nairobi School of Medicine - Fahari ya Jamii project, Nairobi, Kenya.
Ashford MuneneDepartment of Clinical Medicine and Therapeutics, University of Nairobi School of Medicine - Fahari ya Jamii project, Nairobi, Kenya.
Collins OdhiamboDepartment of Pediatrics, College of Medicine, University of Illinois, Peoria, IL, USA.
Susan ArodiDepartment of Clinical Medicine and Therapeutics, University of Nairobi School of Medicine - Fahari ya Jamii project, Nairobi, Kenya.
Reson MarimaDepartment of Clinical Medicine and Therapeutics, University of Nairobi School of Medicine - Fahari ya Jamii project, Nairobi, Kenya.
Annastacia KumolaUnited States Agency for International Development (USAID), Nairobi, East Africa, Kenya.
Dennis OsiemoUnited States Agency for International Development (USAID), Nairobi, East Africa, Kenya.
Teresa SimiyuUnited States Agency for International Development (USAID), Nairobi, East Africa, Kenya.
Jared MechaDepartment of Clinical Medicine and Therapeutics, University of Nairobi School of Medicine - Fahari ya Jamii project, Nairobi, Kenya.
C F OtienoDepartment of Clinical Medicine and Therapeutics, University of Nairobi School of Medicine - Fahari ya Jamii project, Nairobi, Kenya.

Funding

U.S President's Emergency Plan for AIDS Relief (PEPFAR) Cooperative Agreement Number 72061521CA00014
6 · The paper itself

Abstract

backgroundCervical cancer is the leading cause of cancer-related deaths and the second most common cancer amongst females in Kenya. Women living with HIV (WLHIV) have a six-fold increased risk of developing cervical cancer than women in the general population. As of October 2021, only 23% (34/149) of Fahari ya Jamii (FYJ) project-supported HIV clinics in Nairobi and Kajiado Counties were offering cervical cancer screening for WLHIV. Visual inspection with acetic acid (VIA) positive lesions identified were being treated in only 7% (11/34) of facilities. The project implemented an intervention and sought to determine its outcome on cervical cancer screening and treatment uptake.

methodsThis was a retrospective analysis of data from 1st July 2022 to 30th June 2023. The intervention focused on building the capacity of service providers, determining cervical cancer screening eligibility using Kenya National eligibility screening guidelines, providing screening supplies and commodities, creating service demand through health education by mentor mothers and peer educators, providing screening services and on-site treatment of VIA positive lesions. WLHIV aged 25 to 49 years and receiving care in 64 USAID-FYJ-supported facilities in Nairobi and Kajiado Counties were included in the analyses. Descriptive analyses were performed for sociodemographic characteristics, screening and treatment uptake.

resultsA total of 52% (11,089/21,324) WLHIV received cervical cancer screening services, representing a five-fold increase from pre-intervention figures (2,186). The number of facilities offering screening services increased from 23% (34/149) to 43% (64/149). Of the women screened, 2% (245) VIA positive cervical lesions were identified. Treatment uptake improved from 38% pre-intervention to 90%, with 90% (220/245) of identified cases receiving appropriate treatment. The intervention successfully integrated screening into routine HIV care, facilitated same-day treatment in equipped facilities, and strengthened provider capacity, leading to sustained service delivery improvements.

conclusionsThe intervention increased cervical cancer screening and treatment uptake for VIA positive lesions among WLHIV by integrating services into routine HIV care, enhancing provider training, and ensuring the availability of screening supplies. These findings highlight the potential for scaling up similar strategies in resource-limited settings. Sustained mentorship and continuous monitoring will be essential to further strengthen screening and treatment efforts toward cervical cancer elimination.

Indexed as

Early Detection of CancerHIV InfectionsMass ScreeningUterine Cervical NeoplasmsAcetic AcidAdultFemaleHumansKenyaMiddle AgedRetrospective StudiesAcetic AcidCervical cancer screeningVIA positive lesions treatmentWomen living with HIV

Identifiers

PMID41299522
PMCPMC12750709

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.