Evidence map›Paper›PMID 41299518›Full record

SynthesisBMC oral health2025

Prevalence and risk factors for early childhood caries in North Africa: a systematic review and meta-analysis.

Bamidele Adetokunbo Famurewa, Adetayo Oluwole Aborisade, Anita Mofiyinfolu Dabar, Folahanmi Tomiwa Akinsolu, Maha El Tantawi, Oliver Chukwuemeka Ezechi, Moréniké Oluwátóyìn Foláyan

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bamidele Adetokunbo FamurewaDepartment of Clinical Sciences, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria. bfamurewa@oauife.edu.ng.
Adetayo Oluwole AborisadeDepartment of Oral Diagnostic Sciences, Bayero University, Kano, Nigeria.
Anita Mofiyinfolu DabarDepartment of Clinical Sciences, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Folahanmi Tomiwa AkinsoluDepartment of Clinical Sciences, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Maha El TantawiDepartment of Clinical Sciences, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Oliver Chukwuemeka EzechiDepartment of Clinical Sciences, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Moréniké Oluwátóyìn FoláyanDepartment of Clinical Sciences, Oral Health Initiative, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly childhood caries (ECC) is a significant public health concern, with its prevalence steadily increasing across Africa. However, the extent of North Africa's contribution to the global burden of ECC remains poorly understood. This study aimed to estimate the prevalence and identify its risk factors in North Africa.

methodsThis systematic review and meta-analysis was registered with PROSPERO on March 7th, 2025and examined studies published between 2000 and March 2025 on the prevalence and risk factors of ECC in North African countries. Five databases were searched. Eligible studies included cross-sectional, cohort, and case-control designs involving children aged 0-5 years. Two independent reviewers extracted data on study and population characteristics, ECC prevalence, mean dmft scores, and associated risk factors. Pooled prevalence estimates were calculated using the DerSimonian-Laird random effects model, with heterogeneity assessed via Tau², I², and Cochran's Q test.

resultsOf the 1690 studies screened, 18 met the eligibility criteria. The pooled prevalence of ECC was 57% (95% CI: 50-64, p < 0.001), and the dmft was 2.95 (95% CI: 1.86-4.67). Marked heterogeneity was observed in the meta-analysis. The 16 risk factors associated with ECC were grouped into sociodemographic factors, dietary factors and habits, oral hygiene/health-related factors, and factors related to the oral microbiome (spoon sharing with household).

conclusionsThere is a high burden of ECC among children residing in North Africa. Local, national, and region-specific preventive policies targeting identified risk factors should be deployed to stem the tide of ECC in North Africa. PROSPERO REGISTRATION ID: CRD420251006590. CLINICAL TRIAL NUMBER: Not Applicable.

Indexed as

Dental CariesAfrica, NorthernChild, PreschoolHumansInfantPrevalenceRisk FactorsAfricaBurden of diseaseCariesMeta-analysisPrevalenceRisk indicatorsSystematic review

Identifiers

PMID41299518
PMCPMC12667124

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.