Evidence map›Paper›PMID 41299508›Full record

ArticlePopulation health metrics2025

Modelling excess mortality from non-communicable diseases during wartime: application to the Gaza Strip, occupied Palestinian territories.

Hanan Abukmail, Zhixi Chen, Zeina Jamaluddine, Sarah Aly, Takeru Igusa, Paul B Spiegel, Francesco Checchi

Abstract read
In one paragraph

Article in Population health metrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hanan AbukmailFaculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK.
Zhixi ChenDepartment of Civil and Systems Engineering, Johns Hopkins Whiting School of Engineering, Baltimore, MD, 21218, USA.
Zeina JamaluddineFaculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK.
Sarah AlyDepartment of Emergency Medicine, Loma Linda University Medical Center, Loma Linda, CA, 92354, USA.
Takeru IgusaDepartment of Civil and Systems Engineering, Johns Hopkins Whiting School of Engineering, Baltimore, MD, 21218, USA.
Paul B SpiegelDepartment of International Health, Center for Humanitarian Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA.
Francesco ChecchiFaculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK. francesco.checchi@lshtm.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with non-communicable diseases (NCDs) face multiple risks of excess mortality during wars. The Gaza Strip's health services have been severely disrupted by Israel's campaign since October 2023. We developed a modelling approach to project NCD excess mortality under three defined scenarios.

methodsWe projected excess mortality from cancer (lung, colorectal, and breast), cardiovascular disease, diabetes mellitus type 1 patients, and chronic kidney disease requiring haemodialysis from February 2024 to August 2024. We defined three scenarios of treatment coverage: (i) ceasefire, (ii) status quo, and (iii) escalation. We used pre-war incidence and prevalence data to probabilistically simulate deaths among patient cohorts exposed to varying time-dependent mortality depending on their treatment status. We subtracted the expected non-crisis mortality based on pre-war data to compute excess deaths.

resultsWe projected 1,680, 2,480 and 2,680 excess deaths under the ceasefire, status quo and escalation scenarios, respectively, from February till August 2024, plus 1489 in the war's earlier phase. Most deaths were projected among individuals aged >50 years old and from ischaemic heart disease.

conclusionTo our knowledge this is the first attempt to project NCD mortality in a live war setting, demonstrating potential impacts on NCD burden, particularly due to cardiovascular causes. The model focusses only on a subset of NCDs and neglects the impact of the crisis on disease progression, thereby plausibly underestimating actual mortality. It could inform better humanitarian resource allocation and service planning but requires refinement and improved parameterisation.

Indexed as

Noncommunicable DiseasesWarfareAdultAgedArmed ConflictsCardiovascular DiseasesFemaleHumansIsraelMaleMiddle AgedMiddle EastMortalityNeoplasmsRenal Insufficiency, Chronic

Identifiers

PMID41299508
PMCPMC12659381

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.