Evidence map›Paper›PMID 41299466›Full record

SynthesisBMC surgery2025

Cardiac rehabilitation for elderly patients undergoing coronary artery bypass grafting: a systematic review and Meta-Analysis.

Juan Huang, Changhong Liu, Jiaxiang Xie, Juan Han

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Juan HuangDepartment of Cardiovascular and Vascular Surgery, The First Affiliated Hospital with Nanjing Medical University, No. 300 Guangzhou Road, Nanjing, China.
Changhong LiuDepartment of Cardiovascular and Vascular Surgery, The First Affiliated Hospital with Nanjing Medical University, No. 300 Guangzhou Road, Nanjing, China. hj20200122@sina.com.
Jiaxiang XieDepartment of Cardiovascular and Vascular Surgery, The First Affiliated Hospital with Nanjing Medical University, No. 300 Guangzhou Road, Nanjing, China.
Juan HanDepartment of Cardiovascular and Vascular Surgery, The First Affiliated Hospital with Nanjing Medical University, No. 300 Guangzhou Road, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac rehabilitation (CR) has been shown to improve outcomes in patients undergoing coronary artery bypass grafting (CABG); however, its specific effects on elderly CABG patients remain unclear. This meta-analysis aims to evaluate the benefits of CR for elderly patients undergoing CABG.

methodsA comprehensive search was conducted across PubMed, Embase, the Cochrane Library, the Cumulative Index to Nursing and Allied Health Literature, China National Knowledge Infrastructure, and Wanfang Data databases for prospective studies on CR interventions in elderly CABG patients, from study inception through February 19, 2025. Two independent researchers screened articles that met the inclusion criteria. Key outcomes included all-cause mortality, cardiovascular mortality, all-cause hospitalization, health-related quality of life (HRQoL), and functional capacity. Meta-analysis was performed using Review Manager 5.3 software.

resultsSix studies involving 621 patients were included. Interventions lasted between 6 and 12 weeks, with follow-up durations ranging from 6 weeks to 6 months. None of the studies reported data on all-cause mortality, cardiovascular mortality, or all-cause hospitalization. Meta-analysis of HRQoL showed no significant improvements in either the physical component summary (WMD: 5.92 [-0.26, 12.1], p = 0.08) or the mental component summary (WMD: 5.92 [-0.14, 1.80], p = 0.28). However, individual studies suggested potential benefits of CR in specific functional domains.

conclusionThis meta-analysis found no statistically significant improvements in the physical or mental health components of HRQoL following CR in elderly CABG patients, based on limited short-term evidence. Some studies indicated potential benefits in functional capacity and physical activity adherence. Clinicians should consider individualized CR programs while acknowledging the existing evidence gaps. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD420251017085.

Indexed as

Cardiac RehabilitationCoronary Artery BypassCoronary Artery DiseaseAgedHumansQuality of LifeCardiac rehabilitationCoronary artery bypass graftingElderlyHealth-related quality of life

Identifiers

PMID41299466
PMCPMC12659137

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.