Evidence map›Paper›PMID 41299394›Full record

ArticleBMC surgery2025

Infective endocarditis after splenectomy for ovarian cancer: a case report.

Luxin Ye, Xuening Wang, Qian Zhao, Xianzhong Cheng, Yourong Chen, Bifang Zhou, Jin Liu, Jing Ni, Xiaoxiang Chen

Abstract readCase Reports
In one paragraph

Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luxin Ye *Department of Gynecologic Oncology, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, 42# Baiziting street, Nanjing, Jiangsu, 210009, People's Republic of China.
Xuening Wang *Department of Gynecologic Oncology, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, 42# Baiziting street, Nanjing, Jiangsu, 210009, People's Republic of China.
Qian ZhaoDepartment of Gynecologic Oncology, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, 42# Baiziting street, Nanjing, Jiangsu, 210009, People's Republic of China.
Xianzhong ChengDepartment of Gynecologic Oncology, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, 42# Baiziting street, Nanjing, Jiangsu, 210009, People's Republic of China.
Yourong ChenDepartment of Gynecologic Oncology, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, 42# Baiziting street, Nanjing, Jiangsu, 210009, People's Republic of China.
Bifang ZhouDepartment of Gynecologic Oncology, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, 42# Baiziting street, Nanjing, Jiangsu, 210009, People's Republic of China.
Jin LiuDepartment of Geriatrics, The Second Affiliated Hospital of Nanjing Medical University, 121# Jiangjiayuan road, Nanjing, Jiangsu, 210011, People's Republic of China.
Jing NiDepartment of Gynecologic Oncology, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, 42# Baiziting street, Nanjing, Jiangsu, 210009, People's Republic of China. nijingwulin@126.com.
Xiaoxiang ChenDepartment of Gynecologic Oncology, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, 42# Baiziting street, Nanjing, Jiangsu, 210009, People's Republic of China. cxxxxcyd@gmail.com.

Funding

Clinical Science and Technology Climbing Program-"Spark"Basic Research Project, The Affiliated Cancer Hospital of Nanjing Medical University ZJ202213Jiangsu Provincial Scientific Research and Health Project ZD2022005Jiangsu Provincial Scientific research and Health Project for Women and Children F202004National Natural Science Foundation of China 82302974Natural Science Foundation of Youth Fund Projects of Jiangsu Province BK20210976Research Project of Jiangsu Cancer Hospital RCQY202402
6 · The paper itself

Abstract

backgroundSplenectomy is a common procedure for cytoreductive surgery in ovarian cancer. Secondary infective endocarditis after splenectomy for malignancy has not been previously reported. CASE PRESENTATION: A 54-year-old female patient who underwent splenectomy for cytoreductive surgery of ovarian cancer had an elevated postoperative white blood cell (WBC) count and subsequent intestinal obstruction. Echocardiography revealed vegetation on the mitral valve leaflet, and next-generation sequencing identified Gemella morbillorum in the blood. Subsequently, she was diagnosed with infective endocarditis and ultimately died from septicemia.

conclusionPostsplenectomy secondary infective endocarditis warrants attention. This requires preoperative proper assessment of tolerance for surgical complications, recognizing the implications of an elevated WBC count after splenectomy, actively managing postoperative intestinal obstruction, and identifying opportunistic infections.

Indexed as

Endocarditis, BacterialGram-Positive Bacterial InfectionsOvarian NeoplasmsPostoperative ComplicationsSplenectomyFatal OutcomeFemaleGemellaHumansMiddle AgedCase reportGemella morbillorumInfective endocarditisOpportunistic infectionOvarian cancerSplenectomy

Identifiers

PMID41299394
PMCPMC12751448

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.