Evidence map›Paper›PMID 41299297›Full record

Trial reportBMC pregnancy and childbirth2025

Best maternal point of visual focusing for minimizing pain and anxiety during second trimester genetic amniocentesis: a randomized trial.

Chayanich Chinanuwatwong, Kittipong Kongsomboon, Tharangrut Hanprasertpong

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chayanich ChinanuwatwongDepartment of Obstetrics and Gynecology, Faculty of Medicine, Srinakharinwirot University, Ongkharak, Nakornnayok, 26120, Thailand.
Kittipong KongsomboonDepartment of Preventive and Social Medicine, Faculty of Medicine, Srinakharinwirot University, Ongkharak, Nakornnayok, 26120, Thailand.
Tharangrut HanprasertpongDepartment of Obstetrics and Gynecology, Faculty of Medicine, Srinakharinwirot University, Ongkharak, Nakornnayok, 26120, Thailand. tharangrut@hotmail.com.ORCID http://orcid.org/0000-0003-0328-5251

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the best maternal point of visual focusing (PVF) for minimizing pain and anxiety during amniocentesis.

methodsA prospective randomized study was conducted to compare pain and anxiety levels assessed by a visual analogue scale (VAS) on anticipated and perceived pain after amniocentesis between three groups of pregnant women who underwent amniocentesis with three different PVF. Differences between means of anticipated and perceived pain in each maternal PVF were also evaluated.

resultsA total of 105 participants were enrolled and randomly assigned to covered maternal eyes, independent PVF and adapted visual reality (VR) groups, respectively. The mean VAS scores of anticipated pain and perceived pain were not significantly different between each different maternal PVF. The mean VAS of perceived pain was significantly lower than that of anticipated pain in all maternal PVF groups. The different mean VAS scores (95% confidence interval: CI) were 1.50 (0.28-2.71), p-value 0.017 in the maternal covered eyes group, 1.17 (0.16-2.18), p-value 0.025 in the independent PVF group and 0.96 (0.06-1.86), p-value 0.037 in the adapted VR group.

conclusionCovered maternal eyes, independent PVF and adapted VR can all be similarly recommended as the best maternal PVF during amniocentesis.

trial registrationSrinakharinwirot ethics committee (SWUEC/E/M-059/2565) and Thai Clinical Trials Registry TCTRID20221022003 (19 October2022).

Indexed as

AmniocentesisAnxietyProcedural PainAdultFemaleHumansPain MeasurementPregnancyPregnancy Trimester, SecondProspective StudiesVisual Analog ScaleYoung AdultGenetic amniocentesisPainPoint of visual focusing

Identifiers

PMID41299297
PMCPMC12750950

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.