Evidence map›Paper›PMID 41299223›Full record

ArticleBMC plant biology2025

Exploring the role of BpPIN3 in hormonal regulation and branching morphogenesis of Betula pendula.

Kun Chen, Zongzheng Xu, Baolong Ge, Zhe Liu, Yi Xie, Jiabao Ji, Xiaoyue Zhang, Jing Jiang

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Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Kun ChenCollege of Life Science, Qilu Normal University, Jinan, Shandong, 250200, China.
Zongzheng XuCollege of Life Science, Qilu Normal University, Jinan, Shandong, 250200, China.
Baolong GeCollege of Life Science, Qilu Normal University, Jinan, Shandong, 250200, China.
Zhe LiuCollege of Life Science, Qilu Normal University, Jinan, Shandong, 250200, China.
Yi XieCollege of Life Science, Qilu Normal University, Jinan, Shandong, 250200, China.
Jiabao JiLiaoning Provincial Research Institute of Poplar, Gaizhou, China.
Xiaoyue ZhangCollege of Life Science, Qilu Normal University, Jinan, Shandong, 250200, China. zxy16645136050@163.com.
Jing JiangState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, 26 Hexing Road, Harbin, 150040, China. jiangjing@nefu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the role of the BpPIN3 gene in transgenic birch (Betula pendula) and its influence on plant growth and development through hormonal modulation. Previous research suggests that auxin distribution may significantly affect branch development; however, the specific mechanisms underlying this process in birch remain poorly understood. To elucidate these mechanisms, we employed a combination of conventional histological techniques, quantitative analysis of endogenous hormones using UPLC-MS/MS, and detailed RNA sequencing of apex and lateral buds from genetically modified lines (overexpressing BpPIN3, repressing BpPIN3, and wildtype).The results revealed a significant upregulation and downregulation of differentially expressed genes (DEGs) associated with various hormonal pathways, with key functional annotation pointing to stress response, lignin metabolism, and biosynthetic processes. Notably, overexpression of BpPIN3 correlated with decreased auxin levels in lateral buds, while repressing BpPIN3 led to increased auxin in apical buds. This study provides critical insights into how BpPIN3 regulates hormone distribution and affects lateral branching in birch, offering a foundational understanding that can inform further research into hormonal control mechanisms in trees.

Indexed as

BetulaPlant Growth RegulatorsPlant ProteinsGene Expression Regulation, PlantIndoleacetic AcidsMorphogenesisPlants, Genetically ModifiedIndoleacetic AcidsPlant Growth RegulatorsPlant ProteinsBetula pendulaCuttingsHormonesPhytohormone signalingStress-related pathwayWGCNA

Identifiers

PMID41299223
PMCPMC12751574

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.