Evidence map›Paper›PMID 41299100›Full record

ArticleNpj imaging2025

A practical prescription for magnetic resonance microscopy in a horizontal bore magnet.

Bibek Dhakal, Benjamin M Hardy, Adam W Anderson, Mark D Does, Junzhong Xu, John C Gore

Abstract read
In one paragraph

Article in Npj imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Endothelial Continuum and Capillary Specialization in Pulmonary Vascular Development.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bibek DhakalVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA. bibek.dhakal@vanderbilt.edu.
Benjamin M HardyVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA.
Adam W AndersonVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA.
Mark D DoesVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA.
Junzhong XuVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA.
John C GoreVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic resonance microscopy (MRM) produces high spatial resolution proton images of biological tissues, plants, and porous media, revealing microstructural details and contrast unattainable by other means. A major challenge in MRM is the low signal-to-noise ratio at high spatial resolutions, as smaller voxels produce smaller MR signals. This necessitates the use of highly sensitive microcoils, high-performance gradient systems, and high magnetic fields. Here, we present a step-by-step prescription for fabricating a cost-effective, flexible microimaging probe system compatible with horizontal bore high-field MRI systems. We demonstrate performance at 15.2 T by acquiring high-resolution (15 μm isotropic voxels) images of ex vivo mouse spinal cord (gray matter SNR 38; 46 h scan) and hippocampus (SNR 67; 45 h scan), clearly resolving microstructural features. Shorter imaging times are possible using compressed sampling. The flexible probe design supports solenoid diameters ranging from < 1 mm up to 10 mm in diameter, offering flexibility for imaging a variety of biological samples at high resolution.

Identifiers

PMID41299100
PMCPMC12658110

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.