Evidence map›Paper›PMID 41299021›Full record

ReviewNpj imaging2025

New insights into radiolabelled siderophores for molecular imaging of bacterial infections.

Katerina Dvorakova Bendova, Kristyna Krasulova, Barbora Neuzilova, Marian Hajduch, Milos Petrik

Abstract readReview
In one paragraph

Review in Npj imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Katerina Dvorakova BendovaInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic.
Kristyna KrasulovaInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic.
Barbora NeuzilovaInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic.
Marian HajduchInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic.
Milos PetrikInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic. milos.petrik@upol.cz.ORCID http://orcid.org/0000-0003-1334-5916

Funding

the Czech Science Foundation grant number 24-14579Lthe Internal Grant Agency of Palacký University IGA LF IGA_LF_2025_006the Ministry of Education, Youth and Sports of the Czech Republic EATRIS-CZ LM2023053the Ministry of Education, Youth and Sports of the Czech Republic Programme EXCELES, ID project no. LX22NPO5103
6 · The paper itself

Abstract

This perspective article aims to provide an update on current trends in the research of radiolabelled siderophores for molecular imaging of bacterial infections. It begins by explaining the importance of developing novel diagnostic tools for infections and addresses the limitations of contemporary methods, including molecular imaging. The discussion then shifts to compounds currently being studied for nuclear imaging, with a focus on radiolabelled siderophores and recent advances in their development. It also provides the latest insights into the structures of siderophores, their utilisation by bacteria and their role in bacterial metabolism, as well as potential for labelling with various radioisotopes. Additionally, it presents the use of radiolabelled siderophores, both naturally occurring and artificial siderophore derivates, for imaging of various bacterial infections.

Identifiers

PMID41299021
PMCPMC12658088

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.