Evidence map›Paper›PMID 41298865›Full record

ArticleScientific reports2025

Effect of early goal directed mobilization on clinical outcomes in mechanically ventilated ICU patients.

Wanzhu Zhang, Peilin Yu, Mengting Yu, Jie Mi

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wanzhu ZhangChongqing Medical University, Chongqing, China.
Peilin YuChongqing Medical University, Chongqing, China.
Mengting YuChongqing Medical University, Chongqing, China.
Jie MiChongqing Medical University, Chongqing, China. 986457073@qq.com.

Funding

Chongqing Education Commission YJG233061The First Afliated Hospital of Chongqing Medical University HLZD2024-02
6 · The paper itself

Abstract

Patients with mechanical ventilation (MV) in the ICU are prone to various complications. It was proved that early mobility was effective, it improve functional status in patients with chronic diseases, and reduce disability. This study aimed to investigate the effects of early goal-directed mobilization (EGDM) on clinical outcomes of MV patients in ICU. Patients with mechanical ventilation in the ICU are generally confined to bed leading to limited mobility that may have detrimental effects on different body systems. EGDM prevents or reduces these effects and improves outcomes in patients following critical illness. The aim of this research is to investigate the effects of EGDM on clinical outcomes of MV patients in ICU. 64 adult patients in the ICU who were undergoing mechanical ventilation assigned into two groups. With one group received conventional early mobilization (admitted to the intensive care unit [ICU] between August 2023 and January 2024), while the other group received EGDM (admitted to the ICU between February 2024 and June 2024). The capacity of mobility (Medical Research Council (MRC)), length of ICU stay, duration of mechanical ventilation, complication, and mortality at ICU discharge. The capacity of mobility was increased (MRC 37.67 ± 10.00 in EGDM vs. 29.67 ± 8.84 in EM, p < 0.001), the duration of mechanical ventilation and hospital stay is shorter Mechanical ventilation time 6.19 ± 3.03 in EGDM vs. 9.64 ± 3.05 in EM, p < 0.001; ICU stay 310.44 ± 3.92 in EGDM vs. 15.47 ± 4.38 in EM, p < 0.001). The implementation of EGDM in the ICU improved mobilization, increased muscle strength, and shortened the duration of hospital stay and mechanical ventilation. Additionally, EGDM improved the clinical outcomes of patients.

Indexed as

Early AmbulationIntensive Care UnitsRespiration, ArtificialAdultAgedCritical CareCritical IllnessFemaleHumansLength of StayMaleMiddle AgedTreatment OutcomeClinical outcomesEarly goal-directed mobilizationIntensive care unitNurse

Identifiers

PMID41298865
PMCPMC12748879

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.