Evidence map›Paper›PMID 41298677›Full record

ArticleScientific reports2025

High risk HPV among HIV positive women with normal and abnormal cervical cytology in Bahir Dar, north west Ethiopia.

Alemayehu Abate, Melkamnesh Azage

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alemayehu AbateResearch Development Directorate, Amhara Public Health Institute, Bahir Dar, PO, Box 477, P. O.Box:79, Ethiopia. alexu2love@gmail.com.
Melkamnesh AzageBiology Department, College of Science, Bahir Dar University, Box 79, Bahir Dar, PO, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer is a malignant tumor that arises from the cells of the uterine cervix, primarily caused by persistent infection with human papillomavirus (HPV). Women living with HIV are at a heightened risk of infection with high-risk HPV types. This study aimed to determine the prevalence and type-specific distribution of HPV among HIV-positive women with cervical cytologic abnormalities in Bahir Dar, northwestern Ethiopia. A facility-based cross-sectional study was conducted among HIV-positive women in this region between January and March 2025. A total of 344 women were enrolled. Of these, 171 (49.7%) had a high-risk HPV (HR-HPV) infection. The type-specific distribution among the positive cases was as follows: HPV16, 37 (21.6%); HPV18, 15 (8.8%); HPV16 with other types, 24 (14.0%); HPV18 with other types, 7 (4.1%); both HPV16 and HPV18, 6 (3.5%); and other high-risk types, 82 (47.9%). Cytological analysis revealed that 81 women (23.55%) had abnormalities, while 263 (76.45%) had normal results. Among the abnormal cases, the findings were: 26 (32.1%) ASC-US, 22 (27.2%) LSIL, 14 (17.3%) ASC-H, 9 (11.1%) LSIL-H, and 10 (12.3%) HSIL. The study also found that HIV-positive women aged 31 and older had significantly higher odds of HR-HPV infection compared to younger women, with the peak risk observed in the 41-50 age group. Additional risk factors included higher parity, an early sexual debut, and having multiple sexual partners. Given the high prevalence of HR-HPV and its strong association with abnormal cytology, targeted preventive measures including enhanced screening, vaccination, and patient education are crucial for HIV-positive women, particularly in low-resource settings like northwestern Ethiopia.

Indexed as

Cervix UteriHIV InfectionsPapillomavirus InfectionsUterine Cervical NeoplasmsAdolescentAdultCross-Sectional StudiesEthiopiaFemaleHumansMiddle AgedPapillomaviridaePrevalenceRisk FactorsYoung Adult

Identifiers

PMID41298677
PMCPMC12658263

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