Evidence map›Paper›PMID 41298637›Full record

ArticleScientific reports2025

An autoencoder and vision transformer based interpretability analysis on the performance differences in automated staging of second and third molars.

Barkin Buyukcakir, Jannick De Tobel, Patrick Thevissen, Dirk Vandermeulen, Peter Claes

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Barkin BuyukcakirDepartment of Electrical Engineering (ESAT) - Processing Speech and Images (PSI), KU Leuven, Leuven, 3000, Belgium. barkin.buyukcakir@kuleuven.be.
Jannick De TobelDepartment of Diagnostic Sciences, Ghent University, Ghent, 9000, Belgium.
Patrick ThevissenImaging and Pathology - Forensic Odontology Department, KU Leuven, Leuven, 3000, Belgium.
Dirk VandermeulenDepartment of Electrical Engineering (ESAT) - Processing Speech and Images (PSI), KU Leuven, Leuven, 3000, Belgium.
Peter ClaesDepartment of Electrical Engineering (ESAT) - Processing Speech and Images (PSI), KU Leuven, Leuven, 3000, Belgium.

Funding

KU Leuven 3E180439
6 · The paper itself

Abstract

The practical adoption of deep learning in high-stakes forensic applications, such as dental age estimation, is often limited by the 'black box' nature of the models. This study introduces a framework designed to enhance both performance and transparency in this context. We use a notable performance disparity in the automated staging of mandibular second (tooth 37) and third (tooth 38) molars as a case study. The proposed framework, which combines a convolutional autoencoder (AE) with a Vision Transformer (ViT), improves classification accuracy for both teeth over a baseline ViT, increasing from 0.712 to 0.815 for tooth 37 and from 0.462 to 0.543 for tooth 38. Beyond improving performance, the framework provides multi-faceted diagnostic insights. Analysis of the AE's latent space metrics and image reconstructions indicates that the remaining performance gap is data-centric, suggesting high intra-class morphological variability in the tooth 38 dataset is a primary limiting factor. This work highlights the insufficiency of relying on a single mode of interpretability, such as attention maps, which can appear anatomically plausible yet fail to identify underlying data issues. By offering a methodology that both enhances accuracy and provides evidence for why a model may be uncertain, this framework serves as a more robust tool to support expert decision-making in forensic age estimation.

Indexed as

Age Determination by TeethForensic DentistryImage Processing, Computer-AssistedMolarMolar, ThirdAutoencoderDeep LearningHumansConvolutional autoencoderDental stage estimationInterpretabilityVision transformer

Identifiers

PMID41298637
PMCPMC12658131

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.