Evidence map›Paper›PMID 41298587›Full record

ArticleScientific reports2025

Exploring the links between sleep quality and stroke risk in older adults.

Yanru Xiang, Mingyue Xia, Chunhu Zhang, Puwei Chen, Mei Huang, Xingping Dai

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yanru XiangXiangya Hospital, Central South University, Jiangxi (National Regional Center for Neurological Diseases) Honggutan District, No. 266 Fenghe North Avenue, Nanchang, 330038, Jiangxi, People's Republic of China.
Mingyue XiaXiangya Hospital, Central South University, Jiangxi (National Regional Center for Neurological Diseases) Honggutan District, No. 266 Fenghe North Avenue, Nanchang, 330038, Jiangxi, People's Republic of China.
Chunhu ZhangXiangya Hospital, Central South University, Jiangxi (National Regional Center for Neurological Diseases) Honggutan District, No. 266 Fenghe North Avenue, Nanchang, 330038, Jiangxi, People's Republic of China.
Puwei ChenXiangya Hospital, Central South University, Jiangxi (National Regional Center for Neurological Diseases) Honggutan District, No. 266 Fenghe North Avenue, Nanchang, 330038, Jiangxi, People's Republic of China.
Mei HuangXiangya Hospital, Central South University, Jiangxi (National Regional Center for Neurological Diseases) Honggutan District, No. 266 Fenghe North Avenue, Nanchang, 330038, Jiangxi, People's Republic of China.
Xingping DaiXiangya Hospital, Central South University, Jiangxi (National Regional Center for Neurological Diseases) Honggutan District, No. 266 Fenghe North Avenue, Nanchang, 330038, Jiangxi, People's Republic of China. Xingpingdai@csu.edu.cn.

Funding

The Mexican Health and Aging Study - IIR01AG018016 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Rebeca Wong · 1999 to 2026
$22.6M
NIA NIH HHS R01 AG018016
6 · The paper itself

Abstract

The aging population faces significant health challenges, with sleep disturbances emerging as a critical yet often overlooked issue. Poor sleep quality is associated with various adverse health outcomes, including higher risks of mental health disorders and cerebrovascular events such as stroke. Understanding the relationships between sleep health, mental health, and stroke risk is essential for developing effective interventions. This study employed a cross-sectional design involving older adults to examine the associations among sleep disturbances, mental health (specifically depressive symptoms), and stroke risk. Participants completed validated questionnaires assessing sleep quality and depressive symptoms. Multivariate logistic regression and structural equation modeling were employed to analyze the data. The analysis revealed that older adults with difficulty falling asleep faced a significantly increased risk of stroke. Additionally, depressive symptoms were found to mediate the relationship between sleep disturbances and stroke risk. These findings highlight the interconnectedness of sleep health and mental health, demonstrating that poor sleep can contribute to higher rates of depression, which in turn increases stroke risk. The results underscore the importance of prioritizing sleep health in clinical practice for older adults. Addressing sleep disturbances is crucial not only for reducing stroke risk but also for enhancing overall well-being. Future research should further investigate the underlying mechanisms, consider sociocultural factors influencing sleep health, and develop targeted interventions to improve both sleep and mental health in this vulnerable population.

Indexed as

Sleep QualitySleep Wake DisordersStrokeAgedAged, 80 and overCross-Sectional StudiesDepressionFemaleHumansMaleMental HealthMiddle AgedRisk FactorsSleepSurveys and QuestionnairesAging populationHealth interventionsOlder adultsSleep disturbancesStroke risk

Identifiers

PMID41298587
PMCPMC12657859

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.