Evidence map›Paper›PMID 41298381›Full record

ReviewLight, science & applications2025

Emerging frontiers in SERS-integrated optical waveguides: advancing portable and ultra-sensitive detection for trace liquid analysis.

Danheng Gao, Jiahao Liu, Xiao Liu, Kang He, Zhanyu Ma, Huan Liu, Jihou Wang, Qihan Zhang, Zhaonan Huang, Meng Luo and 5 more

Abstract readReview
In one paragraph

Review in Light, science & applications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Polymer-Based Multiparameter Sensing Integrated Photonic Chip for Health Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Danheng Gao *State Key Laboratory of Advanced Manufacturing for Optical Systems, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, 130033, China.ORCID http://orcid.org/0009-0001-7859-9215
Jiahao Liu *State Key Laboratory of Advanced Manufacturing for Optical Systems, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, 130033, China.
Xiao LiuState Key Laboratory of Advanced Manufacturing for Optical Systems, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, 130033, China.
Kang HeState Key Laboratory of Advanced Manufacturing for Optical Systems, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, 130033, China.
Zhanyu MaState Key Laboratory of Advanced Manufacturing for Optical Systems, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, 130033, China.
Huan LiuState Key Laboratory of Advanced Manufacturing for Optical Systems, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, 130033, China.
Jihou WangState Key Laboratory of Advanced Manufacturing for Optical Systems, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, 130033, China.
Qihan ZhangState Key Laboratory of Advanced Manufacturing for Optical Systems, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, 130033, China.
Zhaonan HuangState Key Laboratory of Advanced Manufacturing for Optical Systems, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, 130033, China.
Meng LuoState Key Laboratory of Advanced Manufacturing for Optical Systems, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, 130033, China. luomeng@ciomp.ac.cn.
Haoran MengState Key Laboratory of Advanced Manufacturing for Optical Systems, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, 130033, China. menghaoran@ciomp.ac.cn.
Rui DuDivision of Thyroid Surgery, The China-Japan Union Hospital of Jilin University, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, Changchun, 130033, China.
Juntao GaoSchool of Basic Medical Sciences Tsinghua University Biomedicine Hall, Beijing, 100084, China.
Qing WuHeilongjiang Province Key Laboratory of Laser Spectroscopy Technology and Application, Harbin University of Science and Technology, Harbin, 150080, China.ORCID http://orcid.org/0000-0002-8716-7342
Xinghua YangKey Laboratory of In-Fiber Integrated Optics, Ministry of Education, College of Science, Harbin Engineering University, Harbin, 150001, China.

Funding

China Postdoctoral Science Foundation 2023TQ0369China Postdoctoral Science Foundation GZC20232979National Natural Science Foundation of China (National Science Foundation of China) 42327805National Natural Science Foundation of China (National Science Foundation of China) 42406182National Natural Science Foundation of China (National Science Foundation of China) 62205091
6 · The paper itself

Abstract

Surface-Enhanced Raman Scattering (SERS) integrated with optical waveguide sensing offers a transformative approach to overcoming the limitations of conventional SERS techniques, such as complex alignment requirements and limited signal collection efficiency. By leveraging the unique properties of optical waveguides, this integration significantly enhances detection sensitivity, simplifies sensor design, and enables the analysis of ultra-low concentration analytes in trace-volume samples. This review explores the latest advancements in combining diverse optical waveguide architectures with SERS technology, focusing on strategies to optimize the sensing interface and SERS substrate design for maximal Raman signal enhancement. By enabling efficient analyte excitation and enhanced scattered signal collection through waveguide-mediated light-matter interactions, this approach unlocks new possibilities for high-sensitivity Raman detection. Furthermore, we discuss the potential of this integration to drive breakthroughs in fields such as biomedical diagnostics, environmental monitoring, and chemical sensing, paving the way for next-generation, portable and ultra-sensitive sensing platforms.

Identifiers

PMID41298381
PMCPMC12658145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.