Evidence map›Paper›PMID 41298302›Full record

ArticleZoological research2025

Regulation of UBC12 expression and protein neddylation by PINK1 suggests a primate-specific function.

Wei Huang, Ting Xu, Gong-Ke Zhou, Yu-Xuan Li, Chuang-Zhen Lin, Xiu-Sheng Chen, Tong Zhang, Liang Jiang, Yan-Ting Liu, Xin Xiong and 5 more

Abstract read
In one paragraph

Article in Zoological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Species-dependent activities of the PINK1-parkin axis.Translational neurodegeneration · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Wei HuangGuangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China.
Ting XuGuangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China.
Gong-Ke ZhouGuangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China.
Yu-Xuan LiGuangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China.
Chuang-Zhen LinDepartment of Gastroenterology, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510150, China.
Xiu-Sheng ChenGuangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China.
Tong ZhangGuangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China.
Liang JiangGuangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China.
Yan-Ting LiuGuangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China.
Xin XiongGuangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China.
Xue-Ying LiangGuangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China.
Xiang-Yu GuoGuangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China.
Shi-Hua LiGuangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China.
Xiao-Jiang LiGuangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China.
Wei-Li YangGuangdong Key Laboratory of Non-human Primate Research, Key Laboratory of CNS Regeneration (Ministry of Education), GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong 510632, China. E-mail: weiliyang12@jnu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations in PTEN-induced putative kinase 1 (

Indexed as

BrainGene Expression RegulationGene Expression Regulation, EnzymologicProtein KinasesUbiquitin-Conjugating EnzymesAnimalsHumansMicePTEN-Induced Putative KinaseProtein KinasesPTEN-Induced Putative KinaseUbiquitin-Conjugating EnzymesMonkey modelNeddylationParkinson’s diseasePINK1UBC12

Identifiers

PMID41298302
PMCPMC12940719

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.