Evidence map›Paper›PMID 41298268›Full record

ArticleBMJ open2025

Short- and long-term complications after slowly resorbable biosynthetic P4HB mesh (Phasix) implantation in European centres: a protocol paper for a multiregistry study.

Rudolf van den Berg, Marie Wieser, Johannes Jeekel, Cesare Stabilini, José Bueno-Lledó, Ferdinand Köckerling, Grigorios Chatzimavroudis, Lars Nannestad Jørgensen, Benoit Romain, PRS Group (Phasix Research Study Group)

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rudolf van den BergDepartment of Surgery, Erasmus University Medical Centre, Rotterdam, the Netherlands r.vandenberg.4@erasmusmc.nl.ORCID http://orcid.org/0009-0001-8850-6166
Marie WieserDepartment of Digestive Surgery, University of Strasbourg, Hautepierre, Strasbourg, France.ORCID http://orcid.org/0000-0001-7206-1812
Johannes JeekelDepartment of Neuroscience, Erasmus University Medical Centre, Rotterdam, the Netherlands.
Cesare StabiliniDepartment of Surgery, Policlinico San Martino IRCCS and Department of Surgical Sciences, University of Genoa, Genova, Italy.
José Bueno-LledóUnit of Abdominal Wall Surgery, Department of Digestive Surgery, Hospital Universitari I Poltecnic La Fe, Fernando Abril Martorell, Valencia, Spain.
Ferdinand KöckerlingHernia Center, Vivantes Humboldt-Hospital, Academic Teaching Hospital of Charité University Medicine, Berlin, Germany.
Grigorios ChatzimavroudisComplex Hernia and Abdominal Wall Reconstruction Center, European Interbalkan Medical Center, Thessaloniki, Greece.
Lars Nannestad JørgensenDigestive Disease Center Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Benoit RomainDepartment of Digestive Surgery, University of Strasbourg, Hautepierre, Strasbourg, France.
PRS Group (Phasix Research Study Group)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhasix mesh is a fully resorbable synthetic mesh for use in clean and contaminated ventral incisional hernia repairs. Long-term absorbable Phasix mesh appears to be a safe and promising device in incisional hernia repair, with low recurrence rates; however, data on long-term complications after surgery, particularly after the resorption period of the mesh, are scarce. METHODS AND ANALYSIS: This protocol describes a study of several European registries on the use of a Phasix mesh in incisional hernia repair. The primary endpoint of the study is long-term complications at 2-5 year follow-up after mesh implantation, with secondary endpoints including hernia recurrence and complications during short-term follow-up. ETHICS AND DISSEMINATION: Ethical approval was not required for this protocol as the study is based on anonymised registry data collected with prior patient consent in each registry. Each participating registry has its own ethical approval process, and this study will adhere to those regulations. The results will be disseminated through peer-reviewed publications and conference presentations.

Indexed as

Absorbable ImplantsHernia, VentralHerniorrhaphyIncisional HerniaPostoperative ComplicationsSurgical MeshEuropeHumansRecurrenceRegistriesAdult surgeryColorectal surgeryHospitals, Public

Identifiers

PMID41298268
PMCPMC12658504

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.