Evidence map›Paper›PMID 41297969›Full record

ArticleBMJ (Clinical research ed.)2025

Tai chi or cognitive behavioural therapy for treating insomnia in middle aged and older adults: randomised non-inferiority trial.

Parco M Siu, Danny J Yu, Angus P Yu, Francesco Recchia, Shirley X Li, Rachel Ny Chan, Daniel Y Fong, Derwin Kc Chan, Stanley Sc Hui, Ka Fai Chung and 3 more

Registry-linked trialAbstract readEquivalence Trial
In one paragraph

Article in BMJ (Clinical research ed.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04384822 (Efficacy of Tai Chi Versus Cognitive Behavioral Therapy for Insomnia), which is not on this map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04384822 nacompletednot on this map

Efficacy of Tai Chi Versus Cognitive Behavioral Therapy for Insomnia (CBT-I) to Treat Chronic Insomnia in Older Adults: A Randomized Controlled Non-inferiority Trial

TypeinterventionalSponsorThe University of Hong KongRan2020 to 2023Enrolled200ConditionsChronic InsomniaArmsTai Chi Group, CBT-I Group
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Parco M SiuDivision of Kinesiology, School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.ORCID 0000-0002-3548-5058
Danny J YuDivision of Kinesiology, School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Angus P YuDivision of Kinesiology, School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Francesco RecchiaDivision of Kinesiology, School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Shirley X LiDepartment of Psychology, Faculty of Social Sciences, University of Hong Kong, Hong Kong, China.
Rachel Ny ChanLi Chiu Kong Family Sleep Assessment Unit, Department of Psychiatry, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China.
Daniel Y FongSchool of Nursing, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Derwin Kc ChanDepartment of Social Sciences, School of Arts and Social Sciences, Hong Kong Metropolitan University, Hong Kong, China.
Stanley Sc HuiDepartment of Sports Science and Physical Education, Faculty of Education, Chinese University of Hong Kong, Hong Kong, China.
Ka Fai ChungDepartment of Psychiatry, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Jean WooDepartment of Medicine & Therapeutics, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China.
Chenchen WangDivision of Rheumatology, Allergy & Immunology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA.
Michael R IrwinCousins Center for Psychoneuroimmunology and Department of Psychiatry and Biobehavioural Sciences, University of California, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess whether tai chi is non-inferior to cognitive behavioural therapy for insomnia (CBT-I), the first line treatment, for managing chronic insomnia in middle aged and older adults.

designRandomised, assessor masked, non-inferiority trial.

settingA single research site in Hong Kong with participants recruited from the local community between 18 May 2020 and 14 July 2022.

participantsChinese participants aged ≥50 years with chronic insomnia diagnosed according to the

interventionsTai chi and CBT-I interventions were delivered in group format over three months, consisting of one hour sessions twice a week for a total of 24 sessions.

main outcome measuresThe primary outcome was the change in perceived insomnia severity measured by the Insomnia Severity Index after the intervention (month 3) and at 12 month follow-up (month 15). To assess whether tai chi is non-inferior to CBT-I, a threshold of four points was used as the margin of non-inferiority.

results200 participants were randomised (1:1) to receive tai chi (n=100) or CBT-I (n=100). The per protocol principle was adopted. At month 3, the tai chi group showed a reduction of 6.67 (95% confidence interval 5.61 to 7.73) in Insomnia Severity Index scores, while the CBT-I group had a reduction of 11.19 (10.06 to 12.32), resulting in a between group difference of 4.52 (-∞ to 5.81). Tai chi was deemed inferior to CBT-I at month 3 because the upper confidence limit exceeded the non-inferiority margin. At month 15, the reductions for tai chi and CBT-I were 9.51 (8.47 to 10.54) and 10.18 (8.97 to 11.40), respectively, with a between group difference of 0.68 (-∞ to 2.00). At this point, tai chi was considered non-inferior to CBT-I because the upper confidence limit fell within the non-inferiority margin. Results from the intention-to-treat analysis were consistent with the per protocol findings. No adverse events occurred during the intervention period.

conclusionTai chi was inferior to CBT-I at month 3 but non-inferior at month 15. This finding supports the use of tai chi as an alternative approach for the long term management of chronic insomnia in middle aged and older adults.

trial registrationClinicalTrials.gov NCT04384822.

Indexed as

Cognitive Behavioral TherapySleep Initiation and Maintenance DisordersTai JiAgedFemaleHong KongHumansMaleMiddle AgedSeverity of Illness IndexTreatment Outcome

Identifiers

PMID41297969
PMCPMC12651913

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.