SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2025
Short-term and long-term effects of air pollution on acute lower respiratory infections incidence and mortality: an overview and critical appraisal of systematic reviews.
Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Evaluating Elicit's systematic reviews workflow in an umbrella review on air pollution and acute lower respiratory infections: a methodological study for quality appraisal.BMC medical research methodology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute lower respiratory infections (ALRIs) are a significant health concern, particularly affecting children and older adults. Air pollution is a known risk factor. Despite numerous systematic reviews exploring this relationship, varying methodological quality hinders the derivation of reliable concentration-response functions essential for health risk assessment.
methodsWe critically appraised systematic reviews investigating the association between air pollution and ALRI incidence and mortality, evaluating both short-term and long-term effects across age groups. Comprehensive searches were conducted in PubMed and Embase (up to November 2024). Included systematic reviews were evaluated using AMSTAR2-EH (A MeaSurement Tool to Assess systematic Reviews-Environmental Health), assessing methodological quality specific to environmental epidemiology.
resultsAmong 330 unique systematic reviews, 15 met inclusion criteria. Short-term systematic reviews did not meet methodological appraisal standards. Studies on other pollutants, like ozone (O
conclusionsThis overview systematically assessed systematic reviews using AMSTAR2-EH, highlighting methodological gaps, particularly in short-term studies, bias assessment and protocol registration. Overall, the evidence suggests a mild but significant association between short-term exposure to air pollutants and pneumonia incidence, and a stronger, more consistent association between long-term exposure and ALRI incidence and mortality, especially for NO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.