Evidence map›Paper›PMID 41297920›Full record

Trial reportJournal of the International Society of Sports Nutrition2025

How does acute caffeine ingestion affect maximal strength and muscular power in bench press and back squat in resistance-trained men?

Yixuan Ma, Yihao Chen, Li Ding, Yuchun Xiao, Tze-Huan Lei, Matthew Barnes, Li Guo, Yinhang Cao, Olivier Girard

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Acute effects of 3 and 6 mg·KgJournal of the International Society of Sports Nutrition · 2026
    Trial
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yixuan MaSchool of Athletic Performance, Shanghai University of Sport, Shanghai, People's Republic of China.
Yihao ChenDepartment of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Li DingSchool of Athletic Performance, Shanghai University of Sport, Shanghai, People's Republic of China.
Yuchun XiaoPhysical Education Teaching and Research Department, Hunan Institute of Technology, Hengyang, People's Republic of China.
Tze-Huan LeiCollege of Physical Education, Hubei Normal University, Huangshi, People's Republic of China.
Matthew BarnesSchool of Sport, Exercise and Nutrition, Massey University, Palmerston North, New Zealand.
Li GuoSchool of Exercise and Health, Shanghai University of Sport, Shanghai, People's Republic of China.
Yinhang CaoSchool of Athletic Performance, Shanghai University of Sport, Shanghai, People's Republic of China.ORCID 0000-0003-2323-3707
Olivier GirardSchool of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, Australia.ORCID 0000-0002-4797-182X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study examined whether caffeine (4 mg/kg) enhances upper- and lower-body maximal strength and muscular power by increasing muscle recruitment and reducing in ratings of perceived exertion (RPE) and pain perception.

methodsFourteen resistance-trained males completed two randomized trials involving either caffeine ingestion (4 mg/kg) or a placebo. Sixty minutes after ingesting capsule, participants performed maximal strength tests (one-maximum repetition [1RM]) followed by muscular power assessments (bar velocity and power output) at 25%, 50%, 75%, and 90% of 1RM, performing 3, 2, 1, and 1 repetitions, respectively during bench press and back squat. Outcome measured included 1RM, mean and peak velocity, mean and peak power output, surface electromyographic activity of the prime movers, RPE, and pain perception.

resultsCompared to placebo, caffeine significantly increased 1RM in both bench press and back squat, while reducing RPE and pain perception and enhancing root mean square (RMS) activity in the

conclusionIngesting a caffeine capsule at a dose of 4 mg/kg enhances maximal strength by increasing muscle recruitment and reducing RPE and pain perception, with greater improvement observed in the bench press than in the back squat. Caffeine also improves muscular power in both exercises without altering muscle recruitment or subjective perception.

Indexed as

CaffeineMuscle, SkeletalMuscle StrengthResistance TrainingWeight LiftingAdultDouble-Blind MethodElectromyographyHumansMalePain PerceptionPhysical ExertionYoung AdultCaffeineErgogenic aidneuromuscular functionnutritional supplementone-maximum repetitionresistance exercise

Identifiers

PMID41297920
PMCPMC12667307

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.