Evidence map›Paper›PMID 41296869›Full record

ArticleScience advances2025

Urban contact patterns shape respiratory syncytial virus epidemics with implications for vaccination.

Presley Kimball, Jean-Sebastien Casalegno, Pamela P Martinez, Ayesha S Mahmud, Bjorn Sandstede, Rachel E Baker

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Presley KimballDivision of Applied Mathematics, Brown University, Providence, RI, USA.ORCID 0009-0001-8487-1617
Jean-Sebastien CasalegnoHospices Civils de Lyon, Hôpital de la Croix-Rousse, Centre de Biologie Nord, Institut des Agents Infectieux, Laboratoire de Virologie, Lyon, France.ORCID 0000-0003-3271-9856
Pamela P MartinezDepartment of Microbiology, University of Illinois Urbana-Champaign, Champaign, IL, USA.ORCID 0000-0002-3607-0938
Ayesha S MahmudDepartment of Demography, University of California, Berkeley, CA, USA.ORCID 0000-0002-2282-8613
Bjorn SandstedeDivision of Applied Mathematics, Brown University, Providence, RI, USA.ORCID 0000-0002-5432-1235
Rachel E BakerDepartment of Epidemiology, Brown University, Providence, RI, USA.ORCID 0000-0002-2661-8103

Funding

Novel data and approaches for dynamic modeling of human behavior and infectious disease ecologyR35GM156856 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Ayesha Sanchita Mahmud · 2024 to 2026
$1.2M
NIGMS NIH HHS R35 GM156856
6 · The paper itself

Abstract

Urban environments may alter the landscape of disease transmission with implications for control. Yet, it is unclear whether urban-rural differences exist in the dynamics of childhood respiratory diseases, given specific mixing patterns in younger age groups. Here, we leverage county-level data on respiratory syncytial virus (RSV) from the United States to reveal an urban-rural gradient in both the intensity and age structure of the RSV epidemic, where urban locations experience more prolonged epidemics with higher burden in infants (under 1 year of age). We develop a mechanistic epidemiological model to show that these differences can be explained by daycare utilization rates in children under 5. Using our model to consider control measures, we find that expanding seasonal immunization access in urban and rural areas may limit the risk of off season RSV epidemics.

Indexed as

EpidemicsRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsRespiratory Syncytial Virus VaccinesUrban PopulationVaccinationChild, PreschoolHumansInfantInfant, NewbornRural PopulationSeasonsUnited StatesRespiratory Syncytial Virus Vaccines

Identifiers

PMID41296869
PMCPMC12652316

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.