SynthesisPloS one2025
Exercise: The key to enhancing sleep quality and physical function in Parkinson's disease? A systematic review and meta-analysis.
Synthesis in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of wearable devices on gait, balance, and motor function in people with Parkinson's disease: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Efficacy of different exercise modalities for sleep quality in Parkinson's disease: a systematic review and network meta-analysis.Frontiers in physiology · 2026Pooled it
- The effects of neuromuscular electrical stimulation on neurological function, balance, and quality of life in patients with parkinson's disease.Irish journal of medical science · 2026Article
- Physical Activity and Exercise for People with Parkinson's Disease: The Past, Present, and Future.Movement disorders : official journal of the Movement Disorder Society · 2026Review
- Exercise Intervention for REM Sleep Behavior Disorder in Parkinson's Disease: Mechanisms and Implications for Neurorehabilitation.CNS neuroscience & therapeutics · 2026Review
- Review
- Exercise for Non-Motor Symptoms of Parkinson's Disease: An Evidence-Based Review of Clinical Trials, Dosing Considerations, and Mechanistic Insights.Neural plasticity · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parkinson's disease (PD) is a significant neurodegenerative disorder that affects millions of individuals worldwide and currently has limited effective treatment options. Exercise has been proposed as a non-pharmacological intervention to improve both motor and non-motor symptoms in PD. This study aims to systematically review and meta-analyze the impact of exercise interventions on sleep quality and physical functioning in PD patients. A comprehensive search of the literature up to December 15, 2023, identified randomized controlled trials that evaluated exercise interventions in PD patients. The primary outcomes were sleep quality, motor function, balance, gait performance, and quality of life. A total of 62 studies with 3,274 participants were included in the analysis. Exercise interventions led to significant improvements in sleep quality [SMD = -0.55, 95% CI (-0.91, -0.18), p = 0.003], motor capability [SMD = -0.47, 95% CI (-0.66, -0.28), p < 0.01], balance ability [SMD = 0.53, 95% CI (0.33, 0.74), p < 0.0001], gait performance [TUGT: SMD = -0.44, 95% CI (-0.60, -0.29), p = 0.0017; stride velocity: SMD = 0.38, 95% CI (0.15, 0.60), p = 0.001; step length: SMD = 0.32, 95% CI (0.10, 0.54), p = 0.004], and quality of life [SMD = -0.38, 95% CI (-0.73, -0.03), p = 0.04] (p < 0.05). Exercise is an effective intervention for enhancing sleep quality and improving physical function in PD patients. These findings underscore the importance of incorporating exercise into the management strategies for PD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.