ArticleProceedings of the National Academy of Sciences of the United States of America2025
ROPGAP3 interacts with PIN2 and modulates its clustering and trafficking in
Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Guanosine triphosphate (GTP)-hydrolyzing enzyme (GTPase) activating proteins (GAPs) negatively regulate small GTPase-mediated signaling by enhancing GTP to guanosine diphosphate (GDP) hydrolysis. The Rho small GTPase Of Plants (ROP) signaling pathway mediates the auxin-induced inhibition of endocytosis of PIN-FORMED (PIN) auxin efflux transporters. In our quest to find modulators of PIN behavior, we identified ROPGAP3 as a direct interactor of PINs in
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