Evidence map›Paper›PMID 41296724›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Nonionic signaling rapidly remodels postsynaptic DLG to induce retrograde homeostatic plasticity.

Chengjie Qiu, Sarah Perry, Christine Chen, Jiawen Chen, Jin Zhuang, Yifu Han, Pragya Goel, Dion Dickman

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The Effects of CaMembranes · 2026
    Article
  2. Article
  3. Robust PHP in Adult Hippocampus: Essential Assay Optimizations.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chengjie QiuUniversity of Southern California, Department of Neurobiology, Los Angeles, CA 90089.ORCID 0000-0002-5382-8325
Sarah PerryUniversity of Southern California, Department of Neurobiology, Los Angeles, CA 90089.
Christine ChenUniversity of Southern California, Department of Neurobiology, Los Angeles, CA 90089.
Jiawen ChenUniversity of Southern California, Department of Neurobiology, Los Angeles, CA 90089.
Jin ZhuangUniversity of Southern California, Department of Neurobiology, Los Angeles, CA 90089.
Yifu HanUniversity of Southern California, Department of Neurobiology, Los Angeles, CA 90089.ORCID 0000-0002-1201-654X
Pragya GoelUniversity of Southern California, Department of Neurobiology, Los Angeles, CA 90089.
Dion DickmanUniversity of Southern California, Department of Neurobiology, Los Angeles, CA 90089.ORCID 0000-0003-1884-284X

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI KEVIN R COOK · 2014 to 2026
$13.5M
Molecular Mechanisms Governing the Homeostatic Control of Synaptic StrengthR01NS091546 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DICKMAN, DION KAI · 2015 to 2024
$4.3M
HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) NS091548NIH HHS P40 OD018537NINDS NIH HHS R01 NS091546
6 · The paper itself

Abstract

Synapses must be resilient to the challenges they confront during development, experience, disease, and aging. A conserved form of adaptive plasticity, observed at the glutamatergic

Indexed as

Drosophila ProteinsHomeostasisNeuromuscular JunctionNeuronal PlasticitySignal TransductionSynapsesAnimalsDrosophilaDrosophila melanogasterReceptors, GlutamateSynaptic TransmissionTumor Suppressor Proteinsdlg1 protein, DrosophilaDrosophila ProteinsReceptors, GlutamateTumor Suppressor ProteinsDrosophilaglutamate receptorhomeostatic plasticityneuromuscular junctionsynapse

Identifiers

PMID41296724
PMCPMC12684909

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.