ArticlePloS one2025
Maternal adverse childhood experiences and perinatal outcomes: A retrospective inceptive cohort study.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The early interaction of the primary caregiver and the infant with respect to sex, gender and ego-identity.Frontiers in psychology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAdverse childhood experiences (ACEs) are associated with poor health and social outcomes in adulthood. However, research on the relationship between ACEs and perinatal outcomes remains limited, and the effect of cumulative ACEs on perinatal outcomes has not yet been established. This study examines the association between maternal exposure to multiple ACEs and perinatal outcomes. MATERIAL AND
methodsThe study comprised a cohort study of 1,253 women enrolled in the national prenatal healthcare program in Sweden 2012-2013. In early pregnancy and one year after childbirth the women completed a total of 3 questionnaires that included questions on ACEs, mode of delivery, and birth complications. ACEs were grouped as involving 0, 1-3, or ≥4 categories according to previously defined measures. Multiple ordinal logistic regression analyses were used to compare perinatal outcomes across ACE categories adjusted for a minimal sufficient set of confounders as well as sensitivity analyses.
resultsThe women had an average age of 32, and the majority were multiparous, of Swedish origin, highly educated, non-smokers and in a relationship. The proportions of women with adverse childhood experiences in the 0, 1-3, and ≥4 categories were 42%, 46% and 12%, respectively. On the whole, the adjusted odds ratios (aOR) were highest for women exposed to adverse childhood experience in ≥4 categories, with women exposed to 0 as reference, and with aORs for women exposed to 1-3 categories in between. In women with ≥4 ACEs categories, the strongest associations were found for the outcomes emergency Caesarean delivery (aOR 2.02, CI 1.13-3.63), bleeding >1000 ml in connection with Caesarean delivery (aOR 3.54, CI 1.01-12.39), preeclampsia (aOR 4.21, CI 1.73-10.25) and requiring antibiotics (aOR 3.14, CI 1.19-8.32).
conclusionsMultiple ACEs were associated with higher rates of adverse perinatal outcomes. The maternal health services need to identify these individuals and provide extra care to mitigate their risks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.