Evidence map›Paper›PMID 41296594›Full record

ArticleMolecular and cellular biology2026

Karen McMurdie, Allison N Peeney, Melissa A Mefford, Peter Baumann, David C Zappulla

Abstract read
In one paragraph

Article in Molecular and cellular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

  • Update of
    2025
5 · Who and what money

Authors and funding

5 authors.

Karen McMurdieDepartment of Biology, Johns Hopkins University, Baltimore, Maryland, USA.
Allison N PeeneyDepartment of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania, USA.
Melissa A MeffordDepartment of Biology, Johns Hopkins University, Baltimore, Maryland, USA.
Peter BaumannInstitute for Quantitative and Computational Biosciences (IQCB), Johannes Gutenberg University, Mainz, Germany.ORCID 0000-0003-4892-1485
David C ZappullaDepartment of Biology, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0001-8242-3493

Funding

CELLULAR AND MOLECULAR BIOLOGYT32GM007231 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VAN DOREN, MARK B · 1985 to 2020
$18.4M
Telomere maintenance by the telomerase RNA-protein complexR01GM118757 · NIGMS · LEHIGH UNIVERSITY · PI ZAPPULLA, DAVID CLIFFORD · 2017 to 2021
$1.7M
Investigating Telomerase Mechanism by Exploring the RNAR00GM080400 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ZAPPULLA, DAVID CLIFFORD · 2008 to 2010
$745k
Investigating Telomerase Mechanism by Exploring the RNAK99GM080400 · NIGMS · UNIVERSITY OF COLORADO · PI ZAPPULLA, DAVID CLIFFORD · 2007 to 2008
$106k
NIGMS NIH HHS K99 GM080400NIGMS NIH HHS R00 GM080400NIGMS NIH HHS R01 GM118757NIGMS NIH HHS T32 GM007231
6 · The paper itself

Abstract

The telomerase RNA-protein enzyme is critical for most eukaryotes to complete genome copying by extending chromosome ends, thus solving the end-replication problem and postponing senescence. Despite the importance of the fission yeast

Indexed as

RNARNA, FungalSchizosaccharomycesTelomeraseBase SequenceNucleic Acid ConformationPhylogenySchizosaccharomyces pombe ProteinsTelomereRNARNA, FungalSchizosaccharomyces pombe ProteinsTelomerasetelomerase RNATer1 telomerase subunit, S pombeagingcancerlncRNARNARNPTelomerasetelomereyeast

Identifiers

PMID41296594
PMCPMC13058752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.