Evidence map›Paper›PMID 41296445›Full record

ArticleCurrent issues in molecular biology2025

Fermented Porcine Placenta and Its Dipeptides Modulate Cellular Senescence in Human Keratinocytes.

Yea Jung Choi, Minseo Kang, Mu Hyun Jin, Jongbae Kim, Won Kyung Lee, Seok-Seon Roh, Ki Sung Kang, Gwi Seo Hwang, Sangki Park, Sullim Lee

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yea Jung ChoiCollege of Korean Medicine, Gachon University, Seongnam 13120, Republic of Korea.ORCID 0009-0001-9806-9588
Minseo KangDepartment of Life Science, College of Bio-Nano Technology, Gachon University, Seongnam 13120, Republic of Korea.ORCID 0009-0004-0303-3884
Mu Hyun JinScience Research Park, LG Household and Healthcare Ltd., Seoul 07795, Republic of Korea.
Jongbae KimScience Research Park, LG Household and Healthcare Ltd., Seoul 07795, Republic of Korea.ORCID 0009-0006-1321-566X
Won Kyung LeeScience Research Park, LG Household and Healthcare Ltd., Seoul 07795, Republic of Korea.
Seok-Seon RohScience Research Park, LG Household and Healthcare Ltd., Seoul 07795, Republic of Korea.
Ki Sung KangCollege of Korean Medicine, Gachon University, Seongnam 13120, Republic of Korea.
Gwi Seo HwangCollege of Korean Medicine, Gachon University, Seongnam 13120, Republic of Korea.
Sangki ParkScience Research Park, LG Household and Healthcare Ltd., Seoul 07795, Republic of Korea.ORCID 0009-0001-6066-5026
Sullim LeeDepartment of Life Science, College of Bio-Nano Technology, Gachon University, Seongnam 13120, Republic of Korea.ORCID 0000-0002-4187-2177

Funding

Ministry of Trade, Industry and Energy RS-2025-09452988National Research Foundation of Korea RS-2025-02263193
6 · The paper itself

Abstract

Skin aging is primarily driven by oxidative stress, mitochondrial dysfunction, and cell cycle dysregulation. This study investigated the anti-senescence effects of fermented porcine placenta (FPP) and its dipeptides, leucine-glycine (LG) and proline-hydroxyproline (PH), in human epidermal keratinocytes (HEKs), using nicotinamide mononucleotide (NMN) as a reference for nicotinamide adenine dinucleotide (NAD

Indexed as

fermented porcine placentakeratinocyte senescenceLeu–Glymitochondrial regulationNAD+ metabolismoxidative stressPro–Hyp

Identifiers

PMID41296445
PMCPMC12650961

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.