Evidence map›Paper›PMID 41296280›Full record

ArticleGeneral thoracic and cardiovascular surgery2026

Axial deviation of anastomosis: a risk factor for leakage in retrosternal gastric tube reconstruction after esophagectomy.

Takanori Kurogochi, Naoko Fukushima, Takahiro Masuda, Keita Takahashi, Kohei Uno, Masami Yuda, Akira Matsumoto, Takashi Oshiro, Fumiaki Yano, Ken Eto

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Article in General thoracic and cardiovascular surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Takanori KurogochiDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-ku, Tokyo, 105-8461, Japan. ms03kurogochi@jikei.ac.jp.ORCID http://orcid.org/0000-0002-2188-0444
Naoko FukushimaDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-ku, Tokyo, 105-8461, Japan.
Takahiro MasudaDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-ku, Tokyo, 105-8461, Japan.
Keita TakahashiDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-ku, Tokyo, 105-8461, Japan.
Kohei UnoDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-ku, Tokyo, 105-8461, Japan.
Masami YudaDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-ku, Tokyo, 105-8461, Japan.
Akira MatsumotoDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-ku, Tokyo, 105-8461, Japan.
Takashi OshiroDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-ku, Tokyo, 105-8461, Japan.
Fumiaki YanoDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-ku, Tokyo, 105-8461, Japan.
Ken EtoDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishishimbashi, Minato-ku, Tokyo, 105-8461, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough retrosternal route reconstruction is commonly used in esophagectomy, its anatomical constraints may increase the risk of anastomotic leakage because of the compression of reconstructed organs and deformation of the anastomosis. Therefore, this study retrospectively investigated the effect of anastomosis deformation on leakage.

methodsIn this study, 228 patients who underwent esophagectomy with the McKeown method and triangular anastomosis between 2009 and 2022 were included. The postoperative computed tomography images were analyzed to measure the axial deviation of the esophagogastric anastomosis in the coronal (AD-C) and sagittal (AD-S) images. Moreover, the relationship between axial deviation and anastomotic leakage was examined.

resultsNo significant differences were observed between patients with and without anastomotic leakage in terms of patient background, cancer stage, or surgical technique. However, the patients with anastomotic leakage had significantly greater AD-C and AD-S values than those without. Multivariate analysis identified AD-C > 20° as an independent risk factor for anastomotic leakage (odds ratio, 4.93; 95% confidence interval, 2.06-11.92; p < 0.01).

conclusionsThe axial deviation of the esophagogastric anastomosis is a potential risk factor for anastomotic leakage during retrosternal reconstruction. Further studies incorporating three-dimensional imaging and biomechanical analysis are needed to clarify its impact and optimize the anastomotic geometry.

Indexed as

Anastomotic LeakEsophageal NeoplasmsEsophagectomyEsophagusPlastic Surgery ProceduresStomachAgedAnastomosis, SurgicalFemaleHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk FactorsTomography, X-Ray ComputedAnastomotic leakageEsophageal cancerEsophagectomyTriangular anastomosis

Identifiers

PMID41296280

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.