Evidence map›Paper›PMID 41296265›Full record

Observational studyBrain and behavior2025

Impact of Image Interpretation of Carotid Ultrasound Findings on Lipid Management in Patients With Elevated ASCVD Risk.

Xiaochuan Liu, Sichen Yao, Hua Yang, Zhigang Pan

Abstract readObservational Study
In one paragraph

Observational study in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaochuan LiuDepartment of General Practice, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-6605-9262
Sichen YaoDepartment of General Practice, Wujing Community Health Service Center, Shanghai, China.
Hua YangDepartment of General Practice, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhigang PanDepartment of General Practice, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-9733-6170

Funding

Shanghai Municipal Health Commission Key Supported Discipline Construction
6 · The paper itself

Abstract

backgroundThis study aimed to explore the impact of carotid ultrasound finding interpretation by general practitioners (GPs) on patients' lipid management.

methodsThis study is an observational cohort study involving elderly patients aged ≥ 60 years with elevated risk of atherosclerotic cardiovascular disease (ASCVD). Participants were divided into two groups: image interpretation group and routine care group, and then followed for 3 months. Our primary outcome was to explore the between-group differences in low-density lipoprotein (LDL) changes between the two groups at baseline and after 3 months of follow-up. Secondary outcomes included between-group differences in changes of total cholesterol (TC), triglyceride (TG), and high-density lipoprotein (HDL). The Generalized Estimating Equation model was used to calculate interaction p values, β coefficients, and their 95% CIs.

resultsThis study enrolled 338 participants, with 169 in the image interpretation group (age 69.6 ± 5.76 years) and 169 in the routine care group (age 71.59 ± 5.26 years). The between-group difference in LDL change from baseline to follow-up was statistically significant (interaction p = 0.028), with a β coefficient of -0.38 (95% CI -0.71, -0.04), indicating that the image interpretation group had a 0.38 mmol/L greater LDL reduction than the routine care group. This remained significant after adjusting for confounders (interaction p = 0.025, β = -0.38, 95% CI -0.70, -0.05). There were no significant between-group differences observed against changes in TC, HDL, and TG.

conclusionThis study indicated that adding image interpretation of carotid ultrasound results to routine care by GPs significantly improves lipid management in elderly patients with elevated ASCVD risk.

Indexed as

AtherosclerosisCardiovascular DiseasesCarotid ArteriesAgedCohort StudiesFemaleHumansMaleMiddle AgedRisk FactorsTriglyceridesUltrasonographyUltrasonography, Carotid ArteriesTriglyceridescarotid ultrasoundgeneral practitionersimage interpretationlow‐density lipoprotein

Identifiers

PMID41296265
PMCPMC12650798

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.