Evidence map›Paper›PMID 41296123›Full record

SynthesisObesity surgery2025

Thyroid function post-bariatric surgery: an updated systematic review and meta-analysis.

Niloofar Seighali, Alireza Khodayari Javazm, Sina Kazemian, Mohammadhasan Matin, Hedie Soltani, Mahya Beikmohammdi, Amirhossein Mehrpour, Mahmood Bakhtiyari

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Niloofar SeighaliNon-Communicable Disease Research Center, Alborz University of Medical Sciences, Karaj, Islamic Republic of Iran. niloofarseighaly@gmail.com.
Alireza Khodayari JavazmCardiovascular Research Center, Alborz University of Medical Sciences, Karaj, Islamic Republic of Iran. khodayarialireza499@gmail.com.
Sina KazemianTehran Heart Center, Cardiovascular Disease Research Institute, Tehran University of Medical Science, Tehran, Islamic Republic of Iran.
Mohammadhasan MatinStudent Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Islamic Republic of Iran.
Hedie SoltaniStudent Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Islamic Republic of Iran.
Mahya BeikmohammdiStudent Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Islamic Republic of Iran.
Amirhossein MehrpourStudent Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Islamic Republic of Iran.
Mahmood BakhtiyariDepartment of Community Medicine, School of Community Medicine, Alborz University of Medical Sciences, Karaj, Islamic Republic of Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review and meta-analysis aim to comprehensively assess the effect of bariatric surgery on thyroid function. A search of PubMed, Web of Science, and Scopus databases was performed until 19 November 2024. Sixty-seven studies with 8,754 total patients included in our analysis showed a significant decrease in pooled standard mean differences (SMD) of serum TSH, total T3, and free T3 levels post operation (p-value < 0.05). Our analysis showed a significant marginal decrease in total T4 level by subgroup analysis in overall region and surgery (p-value < 0.05) whereas free T4 didn't change significantly (p-value > 0.05). Subgroup analyses, meta-regression, and publication bias analysis were done. Based on this meta-analysis, significant reduction of TSH, marginally total T4, Total T3, and free T3 levels, as well as non-significant change of FT4 are expected following bariatric surgery.

Indexed as

Bariatric SurgeryObesity, MorbidThyroid GlandHumansPostoperative PeriodThyroid Function TestsThyrotropinThyroxineTriiodothyronineThyrotropinThyroxineTriiodothyronineBariatric surgeryMeta-analysisObesityT4Thyroid function

Identifiers

PMID41296123

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.