Evidence map›Paper›PMID 41296059›Full record

Trial reportInternational urogynecology journal2026

Is Absorbable Suture Non-Inferior to Permanent Suture in Sacrospinous Ligament Suspension? A Randomized Controlled Trial.

Kaythi Khin, Anastasiya Holubyeva, Tess Gao, Shaun Adair, Erika Wasenda, Carolyn Botros, Ricardo Caraballo, Laura Dhariwal

Abstract readRandomized Controlled TrialEquivalence Trial
PubMed Publisher
In one paragraph

Trial report in International urogynecology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kaythi KhinDepartment of Urogynecoloy at Atlantic Health System, 435 South Street, Suite 370, Morristown, NJ, 07960, USA. kaythikhindo@gmail.com.ORCID 0009-0000-1684-7423
Anastasiya HolubyevaDepartment of Urogynecology at South Shore University Hospital, Northwell Health, Bay Shore, NY, USA.
Tess GaoDepartment of Urogynecoloy at Atlantic Health System, 435 South Street, Suite 370, Morristown, NJ, 07960, USA.
Shaun AdairDepartment of Urogynecoloy at Atlantic Health System, 435 South Street, Suite 370, Morristown, NJ, 07960, USA.
Erika WasendaDepartment of Urogynecoloy at Atlantic Health System, 435 South Street, Suite 370, Morristown, NJ, 07960, USA.
Carolyn BotrosDepartment of Urogynecoloy at Atlantic Health System, 435 South Street, Suite 370, Morristown, NJ, 07960, USA.
Ricardo CaraballoDepartment of Urogynecoloy at Atlantic Health System, 435 South Street, Suite 370, Morristown, NJ, 07960, USA.
Laura DhariwalDepartment of Urogynecology at Columbia University Irving Medical Center, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisSacrospinous ligament suspension (SSLS) is a common native-tissue prolapse repair procedure. Although effective, 5-year failure rates can approach 70%. Permanent sutures offer durability but carry risks such as erosion and bleeding. Absorbable sutures may reduce these complications, but their efficacy remains uncertain. We hypothesized that absorbable sutures would be non-inferior to permanent sutures in maintaining apical support at 12 months.

methodsWe conducted a randomized controlled trial from January 2023 to January 2025 at a tertiary center. Patients undergoing SSLS were randomized 1:1 to absorbable or permanent sutures. Blinded assessors evaluated outcomes. The primary outcome was POP-Q point C at 12 months. A non-inferiority margin of 2 points in POP-Q point C and standard deviation of 2 were used. Secondary outcomes included composite prolapse recurrence, suture-related complications, and Patient Global Impression of Improvement (PGI-I). To achieve 90% power with α = 0.05, 18 patients per group were required. Fisher's exact, Mann-Whitney U, and Chi-squared tests were used where appropriate.

resultsForty-nine patients were randomized; 41 completed follow-up (23 absorbable, 18 permanent). Median point C was -5 in both groups (p = 0.98). Composite recurrence rates were similar (43.5% absorbable vs 50% permanent, p = 0.68). No suture erosion or granulation was observed. PGI-I improvement in 82.6% of the absorbable and 100% of the permanent group (p = 0.12).

conclusionsAbsorbable sutures were non-inferior to permanent sutures in supporting apical prolapse at 12 months. Both groups demonstrated high rates of patient-reported improvement with low complication rates.

Indexed as

LigamentsPelvic Organ ProlapseSuturesAgedFemaleHumansMiddle AgedSuture TechniquesTreatment OutcomeAbsorbable suturePermanent sutureSacrospinous ligament suspensionSurgical outcomes

Identifiers

PMID41296059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.