Evidence map›Paper›PMID 41295998›Full record

ArticleSurgical endoscopy2026

Roux-en-Y gastric bypass results in long-term durable weight loss and diabetes remission: a single center, > 15 year outcomes.

Luis Pina, Alvin Chang, G Craig Wood, Joseph Nguyen-Lee, Ryan Horsley, Alexandra Falvo, Mark Mahan, Vladan Obradovic, Anthony T Petrick, David M Parker

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Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luis PinaDivision of Bariatric and Foregut Surgery and The Obesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA, 17822, USA.
Alvin ChangDivision of Bariatric and Foregut Surgery and The Obesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA, 17822, USA.
G Craig WoodDivision of Bariatric and Foregut Surgery and The Obesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA, 17822, USA.
Joseph Nguyen-LeeDivision of Bariatric and Foregut Surgery and The Obesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA, 17822, USA.
Ryan HorsleyDivision of Bariatric and Foregut Surgery and The Obesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA, 17822, USA.
Alexandra FalvoDivision of Bariatric and Foregut Surgery and The Obesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA, 17822, USA.
Mark MahanDivision of Bariatric and Foregut Surgery and The Obesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA, 17822, USA.
Vladan ObradovicDivision of Bariatric and Foregut Surgery and The Obesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA, 17822, USA.
Anthony T PetrickDivision of Bariatric and Foregut Surgery and The Obesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA, 17822, USA.
David M ParkerDivision of Bariatric and Foregut Surgery and The Obesity Institute, Geisinger Health System, 100 N Academy Ave, Danville, PA, 17822, USA. dparker@geisinger.edu.ORCID 0000-0002-7722-9079

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRoux-en-Y gastric bypass (RYGB) has been well-established as a metabolic surgical procedure; however, long-term follow-up data is limited. The purpose of this study is to evaluate long-term (> 15 year) outcomes following RYGB.

methodsA retrospective review of RYGB performed at a single COE from 2001-2008 was conducted. Primary outcomes were mean percent total body weight loss (TBWL) (using repeated measures regression), percent with diabetes (compared between insulin and non-insulin using chi-square test), post-RYGB.

resultsDuring the analysis period, there were 2045 patients that underwent RYGB. Ten years or more of follow-up was available for 68% of the patients (n = 1388) and 48% had > 15 years of follow-up (n = 987). Preoperative mean age was 46 (18-72) and BMI (kg/m2) 47.9 (35-82.2). Maximum mean post-RYGB TBWL of 31.8% occurred at 18 months post-operatively. Mean TBWL stabilized at 23% at 10-20 years post-RYGB. Of the 677 patients with pre-operative diabetes, 10% were insulin-dependent post-RYGB. Diabetes remission rates were 54% at 3 years but decreased to 38% at 15 years. The rate of persistent diabetes post-RYGB was higher in pre-operative insulin-treated diabetes (p < 0.0001).

conclusionOur study represents one of the largest studies of long-term follow data for patients undergoing RYGB. Our data demonstrates that RYGB is successful in providing sustained, long-term, weight loss and diabetes remission.

Indexed as

Diabetes MellitusDiabetes Mellitus, Type 2Gastric BypassObesity, MorbidWeight LossAdolescentAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedRemission InductionRetrospective StudiesTreatment OutcomeBariatric surgeryDiabetesGastric bypassWeight loss

Identifiers

PMID41295998

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.