ReviewVeterinary sciences2025
Porcine Epidemic Diarrhea-Virus-Induced Cell Death: Mechanistic Insights and Therapeutic Strategies.
Review in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Mitochondrial quality control: a new mechanism for antiviral therapy.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Porcine epidemic diarrhea virus (PEDV), a member of the family Coronaviridae, markedly increases morbidity and mortality in neonatal piglets, posing a significant threat to the global swine industry. Cell death represents a double-edged sword: it eliminates infected cells and helps maintain host homeostasis, but it contributes to disease development and progression when dysregulated. Numerous coronaviruses have been shown to induce cell death through well-characterized mechanisms; however, the interplay between PEDV and host cell death remains insufficiently defined. This review seeks to comprehensively delineate the molecular mechanisms by which PEDV modulates cell death, focusing on apoptosis, necroptosis, pyroptosis, and their integrated form, PANoptosis. Furthermore, we summarize current therapeutic strategies targeting these pathways, providing a theoretical framework and potential directions for developing interventions against PEDV infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.