Evidence map›Paper›PMID 41295599›Full record

ArticleNanomaterials (Basel, Switzerland)2025

Theranostic Verteporfin-Conjugated Upconversion Nanoparticles for Cancer Treatment.

Oleksandr Shapoval, Vitalii Patsula, David Větvička, Miroslav Šlouf, Martina Kabešová, Taras Vasylyshyn, Ludmila Maffei Svobodová, Magdalena Konefal, Olga Kočková, Jan Pankrác and 3 more

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Oleksandr ShapovalInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague, Czech Republic.ORCID 0000-0002-0588-6256
Vitalii PatsulaInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague, Czech Republic.
David VětvičkaInstitute of Biophysics and Informatics, First Faculty of Medicine, Charles University, Salmovská 1, 120 00 Prague, Czech Republic.
Miroslav ŠloufInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague, Czech Republic.ORCID 0000-0003-1528-802X
Martina KabešováInstitute of Biophysics and Informatics, First Faculty of Medicine, Charles University, Salmovská 1, 120 00 Prague, Czech Republic.
Taras VasylyshynInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague, Czech Republic.ORCID 0000-0002-3762-5624
Ludmila Maffei SvobodováInstitute of Biophysics and Informatics, First Faculty of Medicine, Charles University, Salmovská 1, 120 00 Prague, Czech Republic.
Magdalena KonefalInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague, Czech Republic.ORCID 0000-0001-7704-1546
Olga KočkováInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague, Czech Republic.ORCID 0000-0003-3761-4033
Jan PankrácCenter for Advanced Preclinical Imaging, First Faculty of Medicine, Charles University, Salmovská 3, 120 00 Prague, Czech Republic.
Petr MatoušCenter for Advanced Preclinical Imaging, First Faculty of Medicine, Charles University, Salmovská 3, 120 00 Prague, Czech Republic.ORCID 0000-0002-9353-5842
Vít HerynekCenter for Advanced Preclinical Imaging, First Faculty of Medicine, Charles University, Salmovská 3, 120 00 Prague, Czech Republic.ORCID 0000-0002-1775-2394
Daniel HorákInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague, Czech Republic.ORCID 0000-0002-6907-9701

Funding

Czech Science Foundation 25-16155SNational Institute for Cancer Research LX22NPO5102
6 · The paper itself

Abstract

Photodynamic therapy (PDT) is a highly selective, clinically approved, minimally invasive technique that effectively eliminates cancer cells. Its effectiveness is limited by poor light penetration into tissue and the hydrophobic nature of photosensitizers, highlighting the need for new approaches to treatment. Here, a theranostic upconversion nanoplatform, consisting of a NaYF

Indexed as

imagingnanoparticlespancreatic cancerphotodynamic therapyverteporfin

Identifiers

PMID41295599
PMCPMC12655723

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.