Comparison of Retinal Thickness Measurements Using Optos Monaco and Heidelberg Spectralis OCT Across ETDRS Sectors in Normal Eyes.

Kakarla V Chalam, Lourdes Ceja, Rene Obispo, Minali Prasad, Anny M S Cheng

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Article in Tomography (Ann Arbor, Mich.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 citing paper in PubMed.

Peripheral instability gradient in macular thickness measurements across five optical coherence tomography systems: a prospective cross-sectional study of inter-device agreement and clinical monitoring risk.BMC medical imaging · 2026
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5 authors.

Kakarla V ChalamDepartment of Ophthalmology, Loma Linda University, Loma Linda, CA 92354, USA.ORCID 0000-0002-0004-9416

Lourdes CejaDepartment of Ophthalmology, Loma Linda University, Loma Linda, CA 92354, USA.

Rene ObispoDepartment of Ophthalmology, Loma Linda University, Loma Linda, CA 92354, USA.

Minali PrasadChobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA.ORCID 0000-0003-0596-1903

Anny M S ChengDepartment of Ophthalmology, University of Florida, Gainesville, FL 32605, USA.ORCID 0000-0001-7035-8567

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare retinal thickness measurements obtained with the Optos Monaco and Heidelberg Spectralis optical coherence tomography (OCT) systems across 9 Early Treatment Diabetic Retinopathy Study (ETDRS) sectors in a cohort comprising normal eyes.

methodsPaired OCT scans from 64 eyes of 32 participants with normal retinal findings were acquired on both devices. Thickness measurements were obtained for the central subfield and the inner and outer sectors of the superior, nasal, inferior, and temporal quadrants. Outcomes included mean thickness, mean interdevice difference (Heidelberg minus Monaco), Pearson correlation coefficients, and Bland-Altman analyses. Scatterplots and Bland-Altman plots were constructed to evaluate agreement and assess potential interchangeability.

resultsThe Heidelberg Spectralis yielded significantly greater retinal thickness values than the Optos Monaco in all ETDRS sectors (

conclusionsOptos Monaco and Heidelberg Spectralis exhibit strong linear correlation in retinal thickness measurements but show significant systematic differences. Interchangeable use requires the application of correction factors where segmentation variability may be greater.

Indexed as

RetinaTomography, Optical CoherenceAdultAgedDiabetic RetinopathyFemaleHumansMaleMiddle AgedReference ValuesReproducibility of ResultsHeidelberg Spectralisoptical coherence tomographyOptos Monacoretinal thickness

Identifiers

PMID41295558

DOI10.3390/tomography11110124

PMCPMC12656429

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