Evidence map›Paper›PMID 41295452›Full record

ArticleVaccines2025

Invasive Meningococcal Disease in the Post-COVID-19 Era in South America.

Marco A P Sáfadi, Juan Francisco Falconi, Maria Gabriela Abalos, Lidia Serra, Angela Gentile, Alejandro Diaz, Claudia P Cortes, Rodolfo Villena

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Ongoing Outbreak ofOpen forum infectious diseases · 2026
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marco A P SáfadiDepartment of Pediatrics, Santa Casa de São Paulo School of Medical Sciences, Rua Afonso Braz, 579, Cj 45, São Paulo 04511-011, Brazil.ORCID 0000-0002-4401-9446
Juan Francisco FalconiPfizer, Santiago 7560742, Chile.
Maria Gabriela AbalosPfizer Vaccines, Buenos Aires B1607EEV, Argentina.
Lidia SerraPfizer, Collegeville, PA 19426, USA.
Angela GentileHospital de Niños Dr. Ricardo Gutiérrez, University of Buenos Aires, Buenos Aires C1425EFD, Argentina.ORCID 0000-0002-1072-7700
Alejandro DiazHospital Pablo Tobón Uribe, Medellín 050015, Colombia.ORCID 0000-0003-0525-9276
Claudia P CortesDepartment of Internal Medicine, Universidad de Chile, Santiago 8330015, Chile.ORCID 0000-0001-9101-9783
Rodolfo VillenaDepartment of Pediatrics, Faculty of Medicine, Universidad de Chile, Infectious Disease Unit, Hospital de Niños Dr. Exequiel González Cortés, Santiago 8900000, Chile.ORCID 0000-0001-7829-1387

Funding

Pfizer Inc N/A
6 · The paper itself

Abstract

backgroundDuring the COVID-19 pandemic, reductions in cases of bacterial diseases transmitted via the respiratory route were reported by the Invasive Respiratory Infection Surveillance Consortium. Here, we evaluate the epidemiology of invasive meningococcal disease (IMD) in Argentina, Brazil, Chile, and Colombia during and after the COVID-19 pandemic.

methodsThe epidemiology of meningococcal disease was reviewed in selected South American countries through 2023 from publicly available national surveillance system databases.

resultsThe incidence of IMD decreased substantially in 2020 in Argentina, Brazil, Chile, and Colombia and was followed by a trend of increased disease. Similarly to observations in several European countries, the post-pandemic rebounds in cases of IMD in the four South American countries included in this analysis were mainly caused by serogroup B, that became one of the predominant serogroups causing IMD in all four countries.

conclusionsEnhanced surveillance of IMD, including genomic characterization of strains, is needed to inform public health policymakers and guide future vaccination strategies in the region.

Indexed as

COVID-19disease incidencemeningococcal diseaseNeisseria meningitidisSouth America

Identifiers

PMID41295452
PMCPMC12656551

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.