ArticleJournal of cardiovascular development and disease2025
CaReMe-CKD-HF-Epidemiology of Heart Failure in Chronic Kidney Disease: A Retrospective Analysis of Routine Administrative Data from a German Hospital Network.
Article in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundHeart failure (HF) is a frequent and clinically relevant comorbidity in patients with chronic kidney disease (CKD). Both conditions are closely linked through hemodynamic, neurohormonal, and inflammatory mechanisms, resulting in excess morbidity and mortality. However, nationwide epidemiological data for hospitalized patients with CKD in Germany are scarce. This study aimed to determine the prevalence and outcomes of HF in CKD using a large real-world dataset. MATERIALS AND
methodsWe conducted a retrospective, observational study analyzing administrative data from 87 German hospitals between 2016 and 2022 (
resultsCKD patients with HF were older (76.5 ± 10.8 vs. 71.5 ± 14.3 years, DISCUSSION: In this large, multicenter, real-world cohort, HF was highly prevalent in CKD and associated with substantially increased morbidity and mortality. These findings highlight the considerable public health burden of HF in CKD and the urgent need for targeted prevention and management strategies.
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