Evidence map›Paper›PMID 41295141›Full record

ArticleJournal of fungi (Basel, Switzerland)2025

Divergent Immunomodulatory Roles of Fungal DNA in Shaping Treg and Inflammatory Responses.

Dongmei Li, Idalia Cruz, Yahui Feng, Maha Moussa, Jie Cheng, Digvijay Patil, Alexander Kroemer, Joseph A Bellanti

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dongmei LiDepartment of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC 20057, USA.ORCID 0000-0002-3272-2513
Idalia CruzDepartment of Oncology, Animal Models, Shared Resources, Georgetown University Medical Center, Washington, DC 20057, USA.
Yahui FengLaboratory of Medical Mycology, Jining No. 1 People's Hospital, Jining 272067, China.ORCID 0000-0003-4512-830X
Maha MoussaDepartment of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC 20057, USA.
Jie ChengDepartment of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC 20057, USA.
Digvijay PatilMedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital and the Center for Translational Transplant Medicine, Georgetown University Medical Center, Washington, DC 20057, USA.
Alexander KroemerMedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital and the Center for Translational Transplant Medicine, Georgetown University Medical Center, Washington, DC 20057, USA.
Joseph A BellantiDepartment of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC 20057, USA.ORCID 0000-0002-5038-7202

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI MARCUS S NOEL · 1990 to 2026
$71.5M
LSR-Fortessa upgrade for Shared ResourceS10OD016213 · OD · GEORGETOWN UNIVERSITY · PI CRESWELL, KAREN A · 2013 to 2013
$298k
NCI NIH HHS P30 CA051008NIH HHS S10 OD016213
6 · The paper itself

Abstract

Fungal communities in the gut influence host immunity, yet most studies have focused on cell wall components rather than genetic materials. Here, we explore how fungal genomic DNA (gDNA) from

Indexed as

cGAS-STING pathwayDNA sensingfungal DNAIL-10TLR-9Treg

Identifiers

PMID41295141
PMCPMC12653120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.