Evidence map›Paper›PMID 41295060›Full record

ArticleJournal of functional biomaterials2025

Biopolymer Fibers of High Strength and Enhanced Orientation by the Synergy of High/Low Molecular Weight Chitosans in Hybrid Biomaterials Processed by Gel Spinning.

Tuan Anh Tran, Ingo Doench, Arnaud Kamdem Tamo, Shaghayegh Jahangir, Sofia Marquez-Bravo, Pamela Molina, Martin Helmstaedter, Aliuska Morales Helguera, Christian Gorzelanny, Anayancy Osorio-Madrazo

Abstract read
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In one paragraph

Article in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tuan Anh TranLaboratory of Organ Printing, University of Bayreuth, 95447 Bayreuth, Germany.ORCID 0009-0001-5389-1201
Ingo DoenchLaboratory of Organ Printing, University of Bayreuth, 95447 Bayreuth, Germany.
Arnaud Kamdem TamoLaboratory of Organ Printing, University of Bayreuth, 95447 Bayreuth, Germany.ORCID 0000-0002-8220-8619
Shaghayegh JahangirLaboratory of Organ Printing, University of Bayreuth, 95447 Bayreuth, Germany.
Sofia Marquez-BravoLaboratory for Bioinspired Materials for Biomedical Engineering BMBT, Department of Microsystems Engineering IMTEK, University of Freiburg, 79110 Freiburg, Germany.
Pamela MolinaLaboratory for Bioinspired Materials for Biomedical Engineering BMBT, Department of Microsystems Engineering IMTEK, University of Freiburg, 79110 Freiburg, Germany.ORCID 0000-0001-6829-9190
Martin HelmstaedterDepartment of Nephrology, University Hospital Freiburg, University of Freiburg, 79106 Freiburg, Germany.ORCID 0000-0001-6027-0094
Aliuska Morales HelgueraCenter of Chemical Bioactives, University of Las Villas, Santa Clara 54838, Cuba.ORCID 0000-0003-4781-547X
Christian GorzelannyDepartment of Dermatology and Venerology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-3788-6429
Anayancy Osorio-MadrazoLaboratory of Organ Printing, University of Bayreuth, 95447 Bayreuth, Germany.

Funding

DFG German Research Foundation DFG Emmy Noether Programme, German Research Foundation
6 · The paper itself

Abstract

High-performance spun bionanocomposite fibers, composed of high-molecular-weight chitosan (HMW), low-molecular-weight chitosan "oligomers" (LMW), and cellulose nanofibers (CNFs), were successfully fabricated via gel spinning of viscous aqueous chitosan (CHI) based formulations into a NaOH coagulation bath. The X-ray diffraction (XRD) analysis revealed that the incorporation of cellulose nanofibers contributed to enhance crystallinity of chitosan in spun fibers. The spinning process, which comprised sequential acidic solubilization, basic neutralization, stretching, and drying steps, produced chitosan/CNF composite fibers with high crystallinity, further enhanced by the incorporation of low molecular weight chitosan. The cellulose nanofibers seem to promote CHI crystallization, by acting as nucleation sites for the nucleation and growth of chitosan crystals, with those latter of LMW further enhancing crystallization and orientation due to higher mobility of shorter polymer chains. Two-dimensional XRD patterns demonstrated the preferential alignment of both CNFs and chitosan crystals along the fiber axis. Increasing the proportion of short-chain chitosan led to a reduction of the viscosity of collodion, facilitating the spinning of solutions with higher polymer concentrations. The X-ray diffraction (XRD) analysis revealed that the addition of low-molecular-weight chitosan (LMW), with an intermediate molecular weight Mw of ~4.4 × 10

Indexed as

anisotropic biomaterialsbionanocompositeschitosan of low and high molecular weightfunctional composite fibersgel spinningpolymer crystallization

Identifiers

PMID41295060
PMCPMC12653652

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.